Posted on January 31, 2020 by harvard2thebighouse
This report is the product of a collaboration between a retired professional scientist with dozens of peer-reviewed publications and 30 years of experience in genomic sequencing and analysis, who worked at the Theoretical Biology Division of the Los Alamos National Laboratory and later helped design several ubiquitous bioinformatic software tools, as well as a former NSA counterterrorism analyst. It considers whether the Wuhan Strain of coronavirus (COVID-19) is the result of naturally emergent mutations against the possibility that it may be a bio-engineered strain – directly altered by genetic manipulation, subject to artificially-guided evolutionary selection, or both – most likely released into the public by accident since China’s rate of occupational accidents is about ten-times higher than America’s, and some twenty-times more than Europe’s, the only other regions with high-level virology labs.
Raising the odds of an accidental release, researchers from China’s only BSL-4 lab in Wuhan were reported to have particularly sloppy field research methods, being both bled and peed on by local bats that host coronaviruses remarkably similar to the Wuhan Strain COVID-19. And they’ve also been reported to smuggle used research animals out of their labs, selling them for cash on the street. Perhaps unsurprisingly, in mid February the Chinese Ministry of Science sent out a directive to all its labs emphasizing the important of carefully handling bio-infectious agents and alluding to slack oversight and past lapses, even mentioning coronaviruses specifically.
Mistakes may have been precipitated by the need to quickly finish research that was being rushed for John Hopkins’ Event 201 which was held this past October and meant to gameplan the containment of a global pandemic. Research may also have been hurried due to deadlines before the impending Chinese New Year – the timing of these events point to increased human error, not a globalist conspiracy. Beijing has had four known accidental leaks of the SARS virus in recent years, so there is absolutely no reason to assume that this strain of coronavirus from Wuhan didn’t accidentally leak out as well. This is unlikely to be a plot twist in one of the novels Tom Clancy wrote after he started mailing it in.
Simply and horribly, this is likely to become another Chernobyl or Fukushima – a catastrophic illustration of mankind’s hubris and intransigence clashing with Nature, as fate again reaps a once unimaginably tragic toll.
Given that this outbreak was said to begin in late December when most bat species in the region are hibernating and the Chinese horseshoe bat’s habitat covers an enormous swath of the region containing scores of cities and hundreds of millions people, the fact that this Wuhan Strain of coronavirus, denoted as COVID-19, emerged in close proximity to the only BSL-4 virology lab in China, which in turn was staffed with at least two Chinese scientists – Zhengli Shi and Xing-Yi Ge – both virologists who had previously worked at an American lab which had already bio-engineered an incredibly virulent strain of bat coronavirus – the accidental release of a bio-engineered virus from Wuhan’s virology lab cannot be automatically discounted, especially when the Wuhan Strain’s unnatural genomic signals are considered.
UPDATE 2/14, 3:02am EST: A probable smoking pre-print has been released, by the National Natural Science Foundation of China:
“In summary, somebody was entangled with the evolution of 2019-nCoV coronavirus. In addition to origins of natural recombination and intermediate host, the killer coronavirus probably originated from a laboratory in Wuhan.”
In a predictable turn, that article has been removed and both researchers have since deleted their profiles off of the ResearchGate site completely. Furthering the appearance of a cover-up, back on January 2nd, the Wuhan Institute of Virology’s director sent out a memo forbidding discussion of an “unknown pneumonia in Wuhan” after ordering the destruction of all related lab materials a day earlier, making it abundantly clear that the Chinese government knew about this outbreak long before they took any steps to contain it, or made any public announcement.
These propaganda efforts have been bolstered by possible collusion from American scientists, some of which is detailed below – but also most notably by one Peter Daszak, who had been publishing papers on coronaviruses alongside the primary Chinese person-of-interest, Zhengli Shi, for years. Perhaps most notably, Daszak is listed as a co-author in the paper first documenting the isolation of a coronavirus from a bat that targets the ACE2 receptor – just like COVID-19 – research done in Wuhan’s virology lab and supervised by Zhengli Shi, and led by a second suspect Chinese researcher who you’ll meet below. At best, Daszak is perhaps acting as an unwitting agent of the Chinese government, but regardless holds an enormous conflict-of-interest. And if nothing else, it is wildly irresponsible to speak-out against the possibility that the virus got out of a lab when a natural origin has not been conclusively demonstrated. Daszak’s statement in The Lancet is either incompetence, or is meant to be a smokescreen for the wanton hubris and greed that have fueled the gain-of-function research detailed below: As one possible related project which may have overlapped with this one, coronaviruses have been seen as a viable vector for an HIV vaccine for years – a project with hundreds of millions of dollars dangling over it.
And unfortunately Daszak is far from alone, there are countless “journalists” mindlessly regurgitating statements from the Chinese government and the WHO with no effort to fact-check whatsoever, as well as “scientists” whose real job is running PR for pharmaceutical and research companies who have spent weeks serving China by making extraordinarily misleading and overconfident statements to the public about the origins and capabilities of this virus. And it should be noted that in 2018, the esteemed scientific journal Nature – which has published numerous articles speciously claiming this virus is definitely natural – was revealed to have buckled to censorship demands from the Chinese government, killing over 1,000 articles to placate their Chinese partners.
Many involved in this dissimulation are effectively acting as agents of a foreign government, and they have left most Americans entirely unprepared for the tragedy that’s beginning to occur in our nursing homes and hospitals. If the idea that just maybe this thing came from a lab had been part of the national dialogue from the start – wouldn’t everyone have been much more cautious and open to social distancing and other limitations once the need arose?
And so being an offshoot of this sort of vaccine program, possibly as a Red Team designed to build defenses and therapeutics against, is just one possible gain-of-function pursuit that would fit some of the unusual genomic and logistical picture below. Whether or not it was the exact target of the Wuhan lab’s genomic tinkering – the reality is millions of dollars of funding from multiple world governments have poured into this research, funding that’s dangled over these scientists as they’ve chased it like Icarus, this time not just risking their own lives – but hundreds of millions of others as well.
Subsequently, we are calling for an immediate end to dual-use gain-of-function research.
– In 2002, Stony Brook first assembled a DNA virus from scratch, building a polio-virus, and providing proof-of-concept for the creation, alteration, and manipulation of DNA-virus genomes. Two years prior, a separate team had already built an simpler RNA-virus from scratch – choosing to engineer a coronavirus from the ground up, and even swapping out its vital spike-protein genes to make it more infectious. And a generation earlier, artificially enhancing selection by intentionally infecting countless series of lab animals with different viruses is understood to have created the H1N1 Swine Flu. Its Franken-genome has a mysterious untraceable genetic parentage and a “clear unnatural origin,” and H1N1 became the poster-child for a moratorium against gain-of-function research – experimentation that seeks to increase a pathogen’s virulence, creating a more effective double-edged sword to counter and learn from. A ban that was in place for years, but was recently lifted by the American government. In the case of H1N1, it wasn’t a question of if it’d escaped from a research laboratory, only whether it’d been designed as part of a weapons system, or been part of a vaccine trial.
– When a virus manages to infect a new species of host it’s known as a zoonotic jump, a process that generally takes months or even years to complete. The first stage is when a virus infects one individual in a new host species, which is typically a dead-end the first time it happens since there’s no way for the virus to be adapted to a different species’ biology. The second stage of a zoonotic jump is when the virus manages to move from the first new host into more hosts of the new species, which results in some temporary transmission in a localized area – these are known as endemics and generally fizzle out the first few times they happen as the virus adapts to its new host species, and mutations win or lose the survival battle. The final stage, the only time a zoonotic jump is considered complete, is when there’s sustained host-to-host transmission in the new species. These zoonotic jumps have some predictable characteristics, the primary one is that adapting to a new host inevitably requires mutations that weren’t optimal in the old host. And so the virus gets weakened as its initially attempting to jump into a new host species, which is why the above sequence of steps – one new host, a few new hosts that pass it among themselves temporarily, and then finally sustained transmission – takes at least several months if not years to play out, since a good bit of time is required for all three steps to occur. Viral trial-and-error is required for the virus to find the right mutations that will allow it to prosper in a new host species, it’s never been known to just happen magically all at once.
– And so assuming that COVID-19 emerged naturally in a matter of weeks in the middle of a massive urban metropolis the size of New York City, when the host population of bats was hibernating anyways, requires completely ignoring everything we know about how viruses transfer between species. Not only was Wuhan’s population not interacting with bats since they hardly interact with humans in urban situations to begin with, but any possible host bats were sleeping in their caves anyways. And not only would the circumstances of this transfer require rewriting the textbooks on zoonotic jumps if it occurred it all, but beyond that: supposedly not only did a zoonotic jump happen instantly without the necessary steps, but when it hit humans it was extraordinarily virulent from the start, something that’s supposed to take an extensive amount of time to ever happen as mutations go through selective trial-and-error. This trial-and-error takes time and is why viruses have never made a zoonotic jump and been instantly virulent in a new host species like COVID-19 has been in humans. Nothing we know about how viruses naturally make zoonotic jumps point to that happening here.
– Tinkering with viral genomes is not anything new, but is not something that has ever been fully embraced by the scientific community at large. About a decade ago, two separate research teams successful tweaked the genome of the H5N1 Bird Flu in just two spots and then passed it through ferrets until it became both airborne and pathogenic to mammals, creating a virus that “could make the deadly 1918 pandemic look like a pesky cold.” This involved selecting for a mutation that allowed the virus to access a receptor that’s found in ferret lungs, and was alarming enough that the research was urged to be published without revealing the specific methods involved and data collected – however it appears that only the most technical details were left out, and most of the research is freely available.
– By 2015, conducting research that was met with an enormous amount of concern, scientists at UNC had successfully created a “chimeric, SARS-like virus” by altering the viral genome of a Chinese bat coronavirus’s spike-protein genes – sequences that code for the spikes that poke out from surface of viruses and allow them to unlock entry into hosts, in this case making the bio-engineered coronavirus incredibly contagious. This research raised eyebrows since it was clearly gain-of-function research, a practice banned in America from 2014 until December 2017 when NIH lifted the ban, specifically to allow research on this sort of virus. Looking at UNC’s gain-of-function research on coronavirus spike-proteins, which received its funding just before the ban was implemented and was only allowed to go forward following a special review, a virologist with the Louis Pasteur Institute of Paris warned: “If the [new] virus escaped, nobody could predict the trajectory.”
– But then oddly, in late January right as the pandemic was blooming, Dr. Ralph Baric claimed in an interview that people should be more concerned with the seasonal flu – despite having personally overseen the controversial engineering of a hyper-virulent strain of batty coronavirus just a few years back. Immediately discounting the burgeoning outbreak of an unknown coronavirus as a non-event seems particularly troubling for someone who’d trained two Chinese scientists on how to make hyper-virulent coronaviruses, especially when it’s hard to imagine that Dr. Baric was unaware his past colleagues were now working at the Wuhan Virology Lab, the epicenter of the outbreak. Highlighting the dissembling absurdity of this statement, based on reporting from Who: the Wuhan Strain COVID-19 appears to be thirty-four times more lethal than the seasonal flu.
– Scientists have expressed concern about China’s ability to safely monitor this BSL-4 lab in Wuhan since it opened in 2017: “an open culture is important to keeping BSL-4 labs safe, and he questions how easy this will be in China, where society emphasizes hierarchy. ‘Diversity of viewpoint, flat structures where everyone feels free to speak up and openness of information are important.'” This lab is at most 20 miles from the wet market where the virus had been assumed to have jumped from animal to human. However the idea that a Chinese lab could have a viral sample escape is well-documented – as mentioned, one lab in Beijing has had four separate incidents of the SARS virus leaking out accidentally.
– Notably, the first three known cases from early December had no contact with that market, and roughly one-third of the initial exposed cohort had no direct ties to Wusan’s wild meat wet-market, the original presumptive source of the virus. And in mid February, reporting indicated that COVID-19’s patient zero in fact had no connection at all with the wet-market. This is reinforced by the fact Chinese research has also concluded that COVID-19 “may have begun human-to-human transmission in late November from a place other than the Huanan seafood market in Wuhan.”
– Since its discovery, scientists have been unable to fully determine the zoological origins of COVID-19, it was initially thought to have passed through snakes, but now all that’s agreed upon is that it’s mostly bat in origin. This inability to derive an exact zoological source is exactly what would be expected if the virus had been artificially engineered to target humans as UNC already has, this doesn’t prove an artificial nature – but it is consistent with one. Although there has been speculation that pangolins may have been the missing vector, the only data about the pangolin virome wasn’t entered into NCBI’s system until late January, and couldn’t possibly have been collected any earlier than late September 2019, and doesn’t fully answer the vector question anyways. And further research indicated it was “very unlikely” that similarities between their spike-protein genomes of COVID-19 and pangolins, where they share the most similarities, was due to the virus passing through pangolins at all.
– As explained in Nature, COVID-19’s Franken-genome combines a cornucopia of distinct genetic markers from each of the three other distinct branches of the coronavirus family tree, but is distinct enough from all of them that it in fact forms its own clade. Along those same lines, a full-genome evolutionary analysis of COVID-19 published in The Lancet concluded, “recombination is probably not the reason for emergence of this virus” since it seems that the Wuhan Strain isn’t a mosaic of previously known coronaviruses, but instead draws from distant, discrete parts of the coronavirus family tree – not how these viruses naturally evolve. Because even mixing and matching coronavirus genomes from every known zoological virus, scientists couldn’t find any possible combination that would explain those regions of the Wuhan Strain’s genome. The Lancet muses that a mysterious animal host could still be out there, however since they’ve already searched through every known possibility and been unable to find a match, another obvious explanation is that bio-engineering accounts for the inexplicable nucleotide signature of the Wuhan Strain’s genome
– Early research found that COVID-19 targets the ACE2 receptor, which seems to be distributed in roughly equal proportions across global populations, indicating that the Wuhan Strain was likely developed as part of a defensive gain-of-function project possibly linked to immunotherapy or vaccinations – never meant to leave the lab, but meant to serve as a Red Team to fight back against, not as an offensive weapon targeting one specific global population. But counter-intuitively, researchers have pointed out that the most critical sections of the COVID-19’s protein-spike genome don’t match the previously reported pattern that would be expected for optimal binding to the specific ACE2 receptors found only in humans and ferrets, which indicates that these particular segments wouldn’t have been directly genetically engineered to increase virulence.
– And yet this is exactly what researchers looking for a “safe” vaccine candidate would engineer, and doesn’t rule out a scenario where the virus was passed through a series of ferrets. The research team in fact notes that its spike “appears to be the result of selection on human or human-like ACE2 permitting another optimal binding solution to arise,” failing to directly mention that the only other human-like receptors are found in ferrets – which have frequently been used for years in vaccine trials for viruses with this sort of protein-spike, and is exactly how the H5N1 Bird Flu virus was altered to make it airborne. And so the Wuhan Strain’s unique affinity for the human ACE2 receptor, which a pre-print reports to be 10 to 20 times greater than SARS, may be the exact type of vaccine-related accident that led to the moratorium on gain-of-function research in the first place and caused scientists to unsuccessfully call for the research around H5N1 to be partially sealed-off.
– The Wuhan Strain of coronavirus, COVID-19, appears to be transmissible even before its host shows any symptoms at all, making temperature-scanning at airports ineffective since hosts appear to be contagious for about a week before any symptoms emerge. This is in stark contrast with SARS, whose hosts weren’t contagious until they were symptomatic, allowing for its relatively quick containment. This chart is not from a peer-reviewed source but was claims to capture the comparative rates of infections between recent outbreaks. A recent pre-print now gives COVID-19 a rating of R4, meaning each host passes the virus on to four new victims, a rate significantly higher than any past global viral outbreak.
– The successful end results of the aforementioned bat coronavirus bio-engineering research at UNC that was critiqued for being too risky in 2015, was published the following year and described the successful bio-engineering of a highly-virulent coronavirus derived from bats which was achieved by tinkering with its spike-protein genes. In this paper, researcher #8 is listed as one “Zheng-li Shi” who’s listed as being attached to the “Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.”
– Zhengli Shi seems to have returned to Wuhan at some point since 2016, specifically to the Wuhan Institute of Virology’s Disease Engineering Technical Research Center, since she then appears in this September 2019 paper on the human behaviors most likely to lead to bat-borne coronavirus exposure in southern China, and also in the paper claiming that this coronavirus was bat in origin, which was peculiarly submitted in coordination with the announcement of the outbreak. Very, very peculiarly. She also appears in this pending preprint on the current outbreak of COVID-19, just a small sample of the dozens of coronavirus-related papers she’s published over a three decade career.
– Not only does Zhengli Shi provide a direct chain of expertise tying the already successful bio-engineering of a virulent bat-based coronavirus at UNC directly to the BSL-4 virology lab in Wuhan, but back in January 2014 she’d received a $665,000 grant from NIH for a study titled The Ecology of Bat Coronaviruses and the Risk of Future Coronavirus Emergence (NIAID R01 AI1 10964) as well as $559,500 more from USAID for a study titled Emerging Pandemic Threats PREDICT_2China (Project No. AID-OAA-A-14-00102). Beyond this American funding specifically into viral diseases zoonotically transferring from animals to humans which would slipped in just before the ban, over the years she’s also received around $3 million in grants to study these zoonotic viruses from China and other countries, and has served on the editorial board of several virological research magazines. More of her research into the intersection of coronaviruses like the Wuhan Strain and their epidemic potential was funded by the U.S. Department of Defense, the U.S. Threat Reduction Agency, and U.S. Biological Defense Research Directorate of the Naval Medical Research Center.
– And so a scientist who’s been prolifically involved with studying the molecular interaction of coronaviruses and humanity, spending decades and millions of dollars, and having even helped build a hyper-virulent coronavirus from scratch at UNC – just so happens to be working at the only BSL-4 virology lab in China that also just so happens to be at the epicenter of an outbreak involved a coronavirus that’s escaping zoological classification, and has other unnatural characteristics that will be discussed below.
– Another Chinese virologist, Xing-Yi Ge, appears as an author on the 2016 UNC paper and is also attached to the lab in Wuhan. Previously in 2013, he’d successfully isolated a SARS-like coronavirus from bats which targets the ACE2 receptor, just like our present virus, the Wuhan Coronavirus COVID-19 uses. And it turns out that sections of the Wuhan Strain’s ACE2 receptor’s genes are unique: they’re almost identical to SARS’s spike-protein genes – despite the fact that almost none of the two coronavirus’s genomes are similar anywhere else at all. Beyond that, although the Wuhan Strain’s spike-protein genome differs from SARS in four out of the five most important genomic spots that determine binding to the ACE2 receptor, they surprisingly don’t effect the protein-spike’s shape. And in an even bigger coincidence, these four spots also code for the outside region of the spike that allows entry into cells, and do not effect it either – allowing the Wuhan Strain to still use the ACE2 receptor to unlock cells while possibly gaining additional capabilities. The odds that this concordance was bio-engineered into the virus are several orders of magnitude more likely than for this to randomly have evolved in nature, and is exactly the sort of process used to make the H5N1 Bird Flu airborne and highly pathogenic.
– Numerous videos purportedly from inside hospitals in Wuhan depict a crisis that is far greater than the numbers released by China to date. There is widespread but unverified online reporting that Wuhan crematoriums have been running 24/7, which is consistent with a recent peer-reviewed study that claims that as of January 25, Wuhan had over 75,000 infections – when the official number was just 761. Chinese language social media also reflects a sense of panic and desperation that is highly discordant with the numbers being released by the Chinese government. Who, notably, are refusing any direct assistance from the American CDC. (Evidence that China is vastly downplaying this pandemic’s severity: Example 1. Example 2. Example 3. Example 4. Example 5. Example 6.)
– Some of the dystopian carnage creeping across China may be due to the fact that much of China’s population may have already been exposed to coronavirus infection via SARS or other less notorious strains, which would allow the Wuhan Stain COVID-19 to use antibody-dependent enhancement (ADE) to much more efficiently enter into cells, and then become much more virulent since this enhancement hijacks the body’s preexisting immune response to coronavirus infections and allows easier entry. However whether or not people have been exposed to a coronavirus infection before, once it’s been circulating in a population for long enough the Wuhan Strain may be able to reinfect its own past hosts and use this molecular hijacking on antibodies left from its own previous infection to become far more virulent, regardless of whether or not someone has been exposed to other coronaviruses before COVID-19. And early reporting from Chinese doctors indicates that re-infections of the Wuhan Strain are far more lethal than the first. More evidence that ADE is occurring is its much higher affinity for the ACE2 receptor and far higher viral loads compared to SARS – both of these may be due at least in part to ADE allowing COVID-19 to much more efficiently bind to and enter cells. And another hint that the Wuhan Strain may be using ADE to more effectively attack its host is the fact that it seems to be targeting its host’s neurological systems, which is explored in depth below. A final clue is the fact that children seem to be far less effected by the Wuhan Strain COVID-19, a phenomenon that’s found in Dengue Fever, which is one of the classic examples for ADE.
– Another peculiar characteristic is COVID-19’s similarities to HIV. And so although another since-retracted pre-print noted several very short genomic sequences in COVID-19’s spike-protein gene that look far more similar to sequences found in HIV than to other coronaviruses – critics quickly pointed out that the shared homology didn’t reach statistical significance. However a closer look at the data reveals that there were a few small shared genomic segments that, despite being physically separated from each other along each strand of DNA, all worked together to code for the Wuhan Strain’s protein-spike’s crucial receptor binding site. Something that is highly unlikely to have happened by chance. And despite most of its protein-spike being shared with SARS, these substituted segments weren’t shared at all – nor were they found in any other coronavirus. One possible but likely reason for these HIV-like segments is that they were meant to be epitopes, or molecular flags meant to mark intruders for a vaccine to target – meaning the Wuhan Strain was built as a monster for a specific vaccine to hunt. It is mathematically possible for this to happen in nature – but only in a ten-thousand bats chained to ten-thousand Petri dishes and given until infinity sense. Alternatively, this pattern could also be produced by infecting a room full of ferrets with a bespoke coronavirus and sifting through the wreckage for your genomic needle.
– Critics have brushed off the Wuhan Strain’s shared homology with HIV as statistically insignificant, however clinical reporting indicates that the Wuhan Strain may be using this shared HIV homology to attack CD4 immune cells just like HIV does, as an unusually high percentage of patients are showing low white blood cell counts, especially the sickest ones. This pathogenicity may well be due to the unique HIV-live genomics of the Wuhan Strain, as one white-paper by LSU’s professor emeritus of Microbiology, Immunology, and Parasitology who’s also a Harvard-educated virologist with a PhD in Microbiology and Molecular Genetics notes: “This is the first description of a possible immunosuppressive domain in coronaviruses… The three key [mutations] common to the known immunosuppressive domains are also in common with the sequence from [the spike-protein]. While coronaviruses are not known for general immunosuppression of the style shown by HIV-1, this does not rule out immunosuppression at the site of active infection in the lung, which would prolong and potentially worsen infection at that site.” And early research has indicated that this unique region may make COVID-19 up to 1,000 times more likely to bind to human cells than SARS, which could be due to either this homology or to ADE, or some combination of these or other factors.
– Even more troubling, a peer-reviewed study noted that one particular part of the Wuhan Strain’s spike-protein genome also wasn’t found in any of its relatives, “and may provide a gain-of-function to [COVID-19] for efficient spreading in the human population.” And according to that paper, this particular type of furin cleavage site makes similar viruses both more pathogenic and more neurotoxic. Additionally, this particular type of cleavage site is a hallmark of being passed through a series of animal hosts in a lab. Evidence for the Wuhan Strain’s neurotoxicity arrived in late February, in a published paper which notes that “the most characteristic symptom of COVID‐19 patients is respiratory distress, and most of the patients admitted to the intensive care could not breathe spontaneously.” Combined with the observation that “some COVID‐19 patients also showed neurologic signs such as headache, nausea and vomiting,” this paper asserts that since SARS was found heavily concentrated in the brainstems of its autopsied victims, COVID-19 is also probably crossing the blood-brain barrier and killing its victims not just via pneumonia, but also by causing neurological respiratory failure. Indicating that ADE may be occurring, but at a much faster rate than nature allows since reinfections of Dengue Fever that use ADE typically have years pass between them.
– And it should be noted that SARS – much ballyhooed as a close relative to the Wuhan Strain – didn’t notable effect white blood cell counts. Additionally, clinical treatment guides published online in late January by established Chinese medical sources note the progressive reduction of white blood cells, as well as the importance of monitoring this decline. And reporting from Thailand indicates that adding a cocktail of two different anti-HIV drugs to the typical flu treatment regime seemed to effectively knock back the Wuhan Strain. Additionally, one of the only autopsies performed outside of China to date found that the deceased had a severely depleted white blood cell count. These lowered counts may come from this shared similarity with HIV, or it could also be the result of ADE as well, since this phenomenon primarily targets white blood cells for its hijackings and may help explain why consecutive infections are so lethal.
– In a highly concerning turn, scientists have noted that the Wuhan Strain can have a “striking” short term rate of mutation which doesn’t indicate an artificial origin but captures the unique threat posed by this coronavirus regardless of its providence, since a faster mutation rates makes it more likely this virus can dodge testing and neutralize vaccines. Something there is already early evidence for. Further concerning are reports out of China that even patients who appear cured still harbor COVID-19 in their system, and although the full implications of this are not yet known – none of them are good.
– One of the worst possible scenarios for COVID-19’s mutation rate would be if it falls into the Goldilocks range that would allow it to form mutant viral swarms: too many mutations will cause a virus to eventually implode, not enough allows host immune systems to catch-up, but if things are just right mutant swarms can form and spread across host populations, burrowing into host nervous systems and causing permanent neurological damage. Mutant swarms form when a virus produces mutationally-damaged copies of itself inside a host, some of which aren’t infectious but find their way into the nervous system where they burrow in causing damage, and others that combine with complimentary broken copies inside host cells to produce working infectious copies of the virus. So a host can not only become crippled with neurological issues, but also still be producing infectious copies of the virus. And it seems as if COVID-19 has many characteristics that indicate the potential to form mutant swarms: the “striking” mutation rate mentioned above and the fact a second widespread mutated strain seems to have already emerged in Washington State with many other isolated strains reported elsewhere, crossing between species is another factor and a dog in Hong Kong appears to have tested positive, the fact that the Wuhan Strain can infect not only the respiratory tract but feces as well – multi-organ involvement is an important contributor to viral swarms, and finally the markedly viral load rate of COVID-19 compared to SARS – SARS produced a viral load several times lower which decreased over time, while COVID-19 produces a “very high” viral load that appears to increase over time and can peak several orders of magnitude higher than SARS was measured to reach. And alarming evidence that this phenomenon is occurring emerged from a Chinese pre-print which noted that over one-third of the roughly 200 patients studied has some neurological symptoms, with nearly half of the most severe patients exhibiting neurological issues. And further evidence for the possibility of both mutant swarms and ADE is witnessed by a study published in Lancet, which notes that the case fatality rate in Wuhan could actually be as high as 20% – the outbreak’s epicenter would be expected to have the highest rates of both phenomena as different variants of the Wuhan Strain infected and reinfected overlapping hosts.
– Another exceptional and atypical trait of the Wuhan Strain COVID-19 is that not only does it form its own clade, it’s calculated to have diverged from SARS and its other sister coronaviruses some 260 years ago. And yet in all that time, while it every other branch of the coronavirus tree was busy branching-off into countless variants, if it emerged naturally, COVID-19 somehow spent a quarter of a millennium as the lone known example of its clade, somehow not mutating into related lineages in all that time. Another simpler explanation is that this apparent hereditary distance and genetic uniqueness is the just the result of being altered in a lab. And although two distinct strains of COVID-19 have been identified, there’s no reason to believe this mutational differentiation happened before contact with humans in the winter of 2019. Additionally, when neutral sites, the specific points in the genome which most reliably show evolutionary change, were examined: COVID-19 looks even more evolutionarily distant from any of its possible relatives, which would make sense if all that evolutionary distance was gained by artificially accelerated generational turn-over in a lab.
– Also giving credence to the idea that the Wuhan Strain was bio-engineered is the existence of a patent application registered to a scientist from Wuhan that looks to modulate a coronavirus’ spike-protein genes – the precise region altered by Zhengli Shi at UNC to make a hyper-virulent strain of coronavirus, and whose alteration and adaptation would explain the Wuhan Strain’s unusual behavior as discussed above.
– And curiously, the head of Harvard’s Chemistry Department, Dr. Charles Lieber, was arrested in the midst of this outbreak on charges that he’d been accepting millions of dollars in bribes from the Chinese government. According to his charging documents, Dr. Lieber first went to the Wuhan University of Technology (WUT), in November 2011 to participate in a nanotechnology forum, which was when he was recruited into a bribery scheme that would net him several million dollars to “establish a research lab and conduct research at WUT,” which became known as ” Joint Nano Key Laboratory,” as well as mentor and advocate for graduate students. By 2015, Dr. Lieber appeared to be fairly intimately involved with what seemed to begin as simply a nanotechnology lab, but now had shifted to involve biology as well, since he described visiting the lab multiple times per year “as we try to build up the nano-bio part of the lab.” Whether or not this nano-bio part of the Nano Key Laboratory is related to Wuhan’s BSL-4 virology lab isn’t clear, however if the Wuhan Strain was bio-engineered, technology classified as “nano-bio” would’ve almost certainly played a role.
Given the above facts, either:
– A coronavirus spontaneously mutated and jumped to humans at a wet market or deep in some random bat cave which just so happened to be 20 miles from China’s only BSL-4 virology lab, a virus with an unusually slippery never-before-seen genome that’s evading zoological classification, that may be as much as twenty-times more contagious than SARS and whose spike-protein region which allows it to enter host cells holds an unique HIV-like signature with the concomitant clinical response, that somehow managed to infect its patient zero who had no connection to this market, and then be so fined-tuned to humans that it’s gone on to create the single greatest public health crisis in Chinese history with approaching 100 million citizens locked-down or quarantined – also causing Mongolia to close its border with its largest trading partner for the first time in modern history and Russia to ban Chinese citizens from entry into their country.
– Or, Chinese scientists failed to follow correct sanitation protocols possibly while in a rush leading up to an international virological conference and during their boisterous holiday season, something that had been anticipated since the opening of the BSL-4 lab and has happened at least four times previously, and accidentally released this bio-engineered Wuhan Strain – likely created by scientists researching immunotherapy regimes against bat coronaviruses, who’ve already demonstrated the ability to perform every step necessary to bio-engineer the Wuhan Strain COVID-19 – into their population, and now the world. As would be expected, this virus appears to have been bio-engineered at the spike-protein genes which was already done at UNC to make an extraordinarily virulent coronavirus. Chinese efforts to prevent the full story about what’s going on from getting out are because they want the scales to be even since they’re now facing a severe pandemic and depopulation event. No facts point against this conclusion.
An immediate international moratorium on all dual-use gain-of-function research must be instated and all existing experimentation must be autoclaved, only greed and hubris have ever been served by attempting this type of genetic manipulation. Humanity does not need a vaccine against HIV derived from a coronavirus, nor do we need to be tinkering with genetic material that holds the potential to wipe a significant percentage of us off the face of the Earth.
Failure to embrace such a ban may effectively become a death sentence for our species, assuming we aren’t already on our last mile.
Saturday, March 21, 2020
Debunking Nature Magazine's "COVID-19 Definitely Didn't Come From A Lab" China Propaganda
Maybe you shouldn’t blindly believe everything you read? Even if the source has a pretty solid reputation?
Nature magazine has censored over 1,000 articles at the request of the Chinese government over the past several years. And it seems pretty clear that their recent article, “The proximal origin of SARS-CoV-2” is just one more example of their influence.
China bought off the head of Harvard’s chemistry department, you don’t think they could buy off run-of-the-mill research scientists scrambling for tenure and funding and publication? It’s absolutely horrific that so many scientists and researchers are taking part in what’s really clearly a disinformation campaign orchestrated by the Chinese Communist Party, and willfully spreading a smokescreen about something that’s already killed thousands and is projected to kill millions more across the planet.
And while the mainstream corporate media mindlessly regurgitates claims from the Chinese government that are falsifiable with the simplest of google searches, allowing the public to be lulled into a false sense of security and complacency, and Reddit rapidly censors and moderates anything that might indicate that this virus leaked from a Chinese lab and so the Chinese government is to blame for this pandemic – sites like ZeroHedge, that have been at the forefront of keeping the lines of investigation open, have been banished from Twitter and marginalized.
Below is a takedown of that article, and the good news is a much more nuanced and honest look at the origins of COVID-19, the Wuhan Strain of coronavirus is just a click away.
Thus, the high-affinity binding of the SARS-CoV-2 spike protein to human ACE2 is most likely the result of natural selection on a human or human-like ACE2 that permits another optimal binding solution to arise. This is strong evidence that SARS-CoV-2 is not the product of purposeful manipulation.
As our report mentions right at the start, scientists passed the H5N1 Bird Flu through a series of ferret hosts until it gained ACE2 affinity and then became incredibly virulent, which is what’s seen with COVID-19 since its affinity to ACE2 is orders of magnitude higher than SARS. That process would leave a genome that appears “natural” and not purposeful as well since it wouldn’t leave a genomic smoking gun and would simply appear to be the result of “natural” selection. However the addition of artificial generations produced by this process of passing through ferrets in the lab would create a lot of genetic distance from any possible relatives – precisely what is seen in COVID-19: it forms its own clade and appears very distant from all other bat coronaviruses. So this is lazy research, they’re either unaware of the Bird Flu study or are willfully ignoring it.
Given the level of genetic variation in the spike, it is likely that SARS-CoV-2-like viruses with partial or full polybasic cleavage sites will be discovered in other species.
This seems like pretty intentional dissimulation. It’s “likely” that other viruses with this cleavage site will be found? What? How likely? 1 in 10? 1 in 10 million? Is it likely that if my aunt grew balls she’d become my uncle? Is it “likely” that a natural intermediate animal vector will be found? Well… likely or not, until it happens it seems incredibly disingenuous to state that “likely” means a damn thing here.
The functional consequence of the polybasic cleavage site in SARS-CoV-2 is unknown, and it will be important to determine its impact on transmissibility and pathogenesis in animal models. Experiments with SARS-CoV have shown that insertion of a furin cleavage site at the S1–S2 junction enhances cell–cell fusion without affecting viral entry14.
This doesn’t seem to address the virus’s provenance at all, but just as an aside it seems like a lot of the viruses with furin cleavage sites engage in ADE, which COVID-19 appears to be doing from a clinical perspective: neurological damage, the second infection is worse, and areas like Wuhan with extended infections have much higher CFRs as infections overlap.
The acquisition of polybasic cleavage sites by HA has also been observed after repeated passage in cell culture or through animals17.
Exactly. Passage through a series of ferret hosts in a lab would have given COVID-19 this distinct cleavage site.
It is improbable that SARS-CoV-2 emerged through laboratory manipulation of a related SARS-CoV-like coronavirus. As noted above, the RBD of SARS-CoV-2 is optimized for binding to human ACE2 with an efficient solution different from those previously predicted7,11.
Yes, again we aren’t arguing that this thing was built nucleotide-by-nucleotide as the perfect bespoke bio-weapon. This efficient solution is exactly the kind of thing that would be selected for after passage through ferrets in lab, which was already done to the Bird Flu that created a horrifically virulent strain. Isn’t it funny that no one’s mentioning that experiment? Or Baric’s work at UNC? How come every single public-facing virologist seems to be leaving these studies out? Are they really unaware of them? That seems exceedingly hard to believe when I was able to find them on the front page of a single google search. Seems a lot more likely everyone’s just covering each other’s asses since they realize the magnitude of what’s happening and how deep into the cover-up they already are.
Furthermore, if genetic manipulation had been performed, one of the several reverse-genetic systems available for betacoronaviruses would probably have been used19
This is an utterly vacuous statement. Probably doesn’t mean a damn thing in science. “Okay folks, we probably won’t get an earthquake anytime soon, so no reason to prepare for one or try and detect one coming!” Seriously?
Instead, we propose two scenarios that can plausibly explain the origin of SARS-CoV-2: (i) natural selection in an animal host before zoonotic transfer; and (ii) natural selection in humans following zoonotic transfer.
As we’ve explained before, there was no trace of this virus before November 2019, and full zoonotic jumps don’t just magically happen, especially not of a virus that’s so incredibly adapted to humans and able to infect us undetected and spread undetected, and then kill us after more than enough time has passed to find multiple new hosts. It’s funny so many virologists are throwing out the book of how zoonotic jumps happen… all that money in gain-of-function research must be quite blinding. Kind of amazing they don’t matter how many thousands of people are dying. As far as the intermediate animal host goes: It might as well be a unicorn at this point. Until someone finds it, it’s just conjecture.
Malayan pangolins (Manis javanica) illegally imported into Guangdong province contain coronaviruses similar to SARS-CoV-221. Although the RaTG13 bat virus remains the closest to SARS-CoV-2 across the genome1, some pangolin coronaviruses exhibit strong similarity to SARS-CoV-2 in the RBD, including all six key RBD residues21 (Fig. 1). This clearly shows that the SARS-CoV-2 spike protein optimized for binding to human-like ACE2 is the result of natural selection.
The most recent study, covered in our article, that examines the neutral sites that are assumed to best show heritage found that pangolins are “very unlikely” to have served as a host at all. Their assertion that natural natural selection is clearly shown is raw steamy bullshit. Serial passage through ferrets fits the overall big picture far better than this pangolin crap.
For a precursor virus to acquire both the polybasic cleavage site and mutations in the spike protein suitable for binding to human ACE2, an animal host would probably have to have a high population density (to allow natural selection to proceed efficiently) and an ACE2-encoding gene that is similar to the human ortholog.
WAIT WAIT WAIT!! You mean exactly like a bunch of ferrets, which have the same ACE2 receptor as humans, all jammed into a bunch of cages together and then infected over and over again in a lab?! That’s crazy talk!! Other than the fact it was exactly the process used to make the Bird Flu into something that “could make the 1918 pandemic look like a pesky cold.”
It is possible that a progenitor of SARS-CoV-2 jumped into humans, acquiring the genomic features described above through adaptation during undetected human-to-human transmission. Once acquired, these adaptations would enable the pandemic to take off and produce a sufficiently large cluster of cases to trigger the surveillance system that detected it.
Hence, this scenario presumes a period of unrecognized transmission in humans between the initial zoonotic event and the acquisition of the polybasic cleavage site. Sufficient opportunity could have arisen if there had been many prior zoonotic events that produced short chains of human-to-human transmission over an extended period.
Sure this would be plausible… other than the fact that, as we cover in our report, that statistical analysis shows that this thing didn’t hit humans until November of 2019, which this article agrees with. But zoonotic jumps only occur after a genomic trial-and-error process where the virus jumps to one host, spreads to a few new hosts, and then fizzles out. There is absolutely no evidence anywhere of this occurring. Every single data points to this thing hitting humans in November and being immediately adapted and dangerous. There is no trace whatsoever of it creating small clusters of infections and dying out – stating there could have been doesn’t mean it’s been seen. It hasn’t. And as our report covers, this would require sustained interaction with the intermediate host – how does that happen in the middle of a massive modern urban metropolis the size of NYC? And where is this intermediate host anyways? If an intermediate host isn’t needed, is it some magical sleep-flying bat that decided not to hibernate and fight crime in Wuhan when it’s buddies were all hibernating, creating the sustained interactions with humans as it fought for Justice? Because that’s about as plausible as what’s being proposed here.
The presence in pangolins of an RBD very similar to that of SARS-CoV-2 means that we can infer this was also probably in the virus that jumped to humans.
Again, analysis of the neutral sites shows that pangolins were almost certainly not in play.
Furthermore, a hypothetical generation of SARS-CoV-2 by cell culture or animal passage would have required prior isolation of a progenitor virus with very high genetic similarity, which has not been described
This means nothing. There is no open-source shared database of viruses. No one has any idea what viruses are in China’s BSL-4 lab, where they’ve been collecting these viruses for years. As mentioned, one of our persons-of-interest was the very first person to isolate a coronavirus from a bat that uses the ACE2 receptor. He also worked at UNC in Baric’s lab making the hyper-virulent bat coronavirus in 2015.
Subsequent generation of a polybasic cleavage site would have then required repeated passage in cell culture or animals with ACE2 receptors similar to those of humans, but such work has also not previously been described.
The fuck it hasn’t.
Retrospective serological studies could also be informative, and a few such studies have been conducted showing low-level exposures to SARS-CoV-like coronaviruses in certain areas of China26. Further serological studies should be conducted to determine the extent of prior human exposure to SARS-CoV-2.
Beyond the statistical analysis that indicates it only hit humans in November in 2019, is the fact that the version of COVID-19 found in the first few dozen hosts was exactly the same – there aren’t any variants whatsoever, just one version. This is not what would be found with the genomic trial-and-error of a full zoonotic jump, which requires sustained human-to-human transmission as different variants of the virus try and fail to adapt to human biology. Here, only one variant was found in all the initial infected humans, instead of the multiple variants that would be expected. But does fit what would happen if a virus that already had high affinity to the ACE2 receptor, which is the same in human and ferrets, leaked out of a lab. But addressing this point in particular, oh weird, the study they cite from March of 2018 was done mostly on people who live in villages barely a kilometer away from bat caves. A far cry from a massive urban city bout the size of NYC. Oh, and how many of these villagers, who live about a kilometer or less from bat caves, had antibodies indicating exposure to bat coronaviruses? Two-point-seven percent. (There is hand-waving about how long antibodies persist in humans, but I’m pretty sure it’s more than long enough.) That study actually sampled people living in Wuhan too and found… no evidence whatsoever of exposure to “SARS-CoV-like coronaviruses.” So are these peer-reviewers just straight chugging lead paint, or are they on the take too?
The finding of SARS-CoV-like coronaviruses from pangolins with nearly identical RBDs, however, provides a much stronger and more parsimonious explanation of how SARS-CoV-2 acquired these via recombination or mutation1
Again, just demonstrably false.
Get the real story here.
Nature magazine has censored over 1,000 articles at the request of the Chinese government over the past several years. And it seems pretty clear that their recent article, “The proximal origin of SARS-CoV-2” is just one more example of their influence.
China bought off the head of Harvard’s chemistry department, you don’t think they could buy off run-of-the-mill research scientists scrambling for tenure and funding and publication? It’s absolutely horrific that so many scientists and researchers are taking part in what’s really clearly a disinformation campaign orchestrated by the Chinese Communist Party, and willfully spreading a smokescreen about something that’s already killed thousands and is projected to kill millions more across the planet.
And while the mainstream corporate media mindlessly regurgitates claims from the Chinese government that are falsifiable with the simplest of google searches, allowing the public to be lulled into a false sense of security and complacency, and Reddit rapidly censors and moderates anything that might indicate that this virus leaked from a Chinese lab and so the Chinese government is to blame for this pandemic – sites like ZeroHedge, that have been at the forefront of keeping the lines of investigation open, have been banished from Twitter and marginalized.
Below is a takedown of that article, and the good news is a much more nuanced and honest look at the origins of COVID-19, the Wuhan Strain of coronavirus is just a click away.
Thus, the high-affinity binding of the SARS-CoV-2 spike protein to human ACE2 is most likely the result of natural selection on a human or human-like ACE2 that permits another optimal binding solution to arise. This is strong evidence that SARS-CoV-2 is not the product of purposeful manipulation.
As our report mentions right at the start, scientists passed the H5N1 Bird Flu through a series of ferret hosts until it gained ACE2 affinity and then became incredibly virulent, which is what’s seen with COVID-19 since its affinity to ACE2 is orders of magnitude higher than SARS. That process would leave a genome that appears “natural” and not purposeful as well since it wouldn’t leave a genomic smoking gun and would simply appear to be the result of “natural” selection. However the addition of artificial generations produced by this process of passing through ferrets in the lab would create a lot of genetic distance from any possible relatives – precisely what is seen in COVID-19: it forms its own clade and appears very distant from all other bat coronaviruses. So this is lazy research, they’re either unaware of the Bird Flu study or are willfully ignoring it.
Given the level of genetic variation in the spike, it is likely that SARS-CoV-2-like viruses with partial or full polybasic cleavage sites will be discovered in other species.
This seems like pretty intentional dissimulation. It’s “likely” that other viruses with this cleavage site will be found? What? How likely? 1 in 10? 1 in 10 million? Is it likely that if my aunt grew balls she’d become my uncle? Is it “likely” that a natural intermediate animal vector will be found? Well… likely or not, until it happens it seems incredibly disingenuous to state that “likely” means a damn thing here.
The functional consequence of the polybasic cleavage site in SARS-CoV-2 is unknown, and it will be important to determine its impact on transmissibility and pathogenesis in animal models. Experiments with SARS-CoV have shown that insertion of a furin cleavage site at the S1–S2 junction enhances cell–cell fusion without affecting viral entry14.
This doesn’t seem to address the virus’s provenance at all, but just as an aside it seems like a lot of the viruses with furin cleavage sites engage in ADE, which COVID-19 appears to be doing from a clinical perspective: neurological damage, the second infection is worse, and areas like Wuhan with extended infections have much higher CFRs as infections overlap.
The acquisition of polybasic cleavage sites by HA has also been observed after repeated passage in cell culture or through animals17.
Exactly. Passage through a series of ferret hosts in a lab would have given COVID-19 this distinct cleavage site.
It is improbable that SARS-CoV-2 emerged through laboratory manipulation of a related SARS-CoV-like coronavirus. As noted above, the RBD of SARS-CoV-2 is optimized for binding to human ACE2 with an efficient solution different from those previously predicted7,11.
Yes, again we aren’t arguing that this thing was built nucleotide-by-nucleotide as the perfect bespoke bio-weapon. This efficient solution is exactly the kind of thing that would be selected for after passage through ferrets in lab, which was already done to the Bird Flu that created a horrifically virulent strain. Isn’t it funny that no one’s mentioning that experiment? Or Baric’s work at UNC? How come every single public-facing virologist seems to be leaving these studies out? Are they really unaware of them? That seems exceedingly hard to believe when I was able to find them on the front page of a single google search. Seems a lot more likely everyone’s just covering each other’s asses since they realize the magnitude of what’s happening and how deep into the cover-up they already are.
Furthermore, if genetic manipulation had been performed, one of the several reverse-genetic systems available for betacoronaviruses would probably have been used19
This is an utterly vacuous statement. Probably doesn’t mean a damn thing in science. “Okay folks, we probably won’t get an earthquake anytime soon, so no reason to prepare for one or try and detect one coming!” Seriously?
Instead, we propose two scenarios that can plausibly explain the origin of SARS-CoV-2: (i) natural selection in an animal host before zoonotic transfer; and (ii) natural selection in humans following zoonotic transfer.
As we’ve explained before, there was no trace of this virus before November 2019, and full zoonotic jumps don’t just magically happen, especially not of a virus that’s so incredibly adapted to humans and able to infect us undetected and spread undetected, and then kill us after more than enough time has passed to find multiple new hosts. It’s funny so many virologists are throwing out the book of how zoonotic jumps happen… all that money in gain-of-function research must be quite blinding. Kind of amazing they don’t matter how many thousands of people are dying. As far as the intermediate animal host goes: It might as well be a unicorn at this point. Until someone finds it, it’s just conjecture.
Malayan pangolins (Manis javanica) illegally imported into Guangdong province contain coronaviruses similar to SARS-CoV-221. Although the RaTG13 bat virus remains the closest to SARS-CoV-2 across the genome1, some pangolin coronaviruses exhibit strong similarity to SARS-CoV-2 in the RBD, including all six key RBD residues21 (Fig. 1). This clearly shows that the SARS-CoV-2 spike protein optimized for binding to human-like ACE2 is the result of natural selection.
The most recent study, covered in our article, that examines the neutral sites that are assumed to best show heritage found that pangolins are “very unlikely” to have served as a host at all. Their assertion that natural natural selection is clearly shown is raw steamy bullshit. Serial passage through ferrets fits the overall big picture far better than this pangolin crap.
For a precursor virus to acquire both the polybasic cleavage site and mutations in the spike protein suitable for binding to human ACE2, an animal host would probably have to have a high population density (to allow natural selection to proceed efficiently) and an ACE2-encoding gene that is similar to the human ortholog.
WAIT WAIT WAIT!! You mean exactly like a bunch of ferrets, which have the same ACE2 receptor as humans, all jammed into a bunch of cages together and then infected over and over again in a lab?! That’s crazy talk!! Other than the fact it was exactly the process used to make the Bird Flu into something that “could make the 1918 pandemic look like a pesky cold.”
It is possible that a progenitor of SARS-CoV-2 jumped into humans, acquiring the genomic features described above through adaptation during undetected human-to-human transmission. Once acquired, these adaptations would enable the pandemic to take off and produce a sufficiently large cluster of cases to trigger the surveillance system that detected it.
Hence, this scenario presumes a period of unrecognized transmission in humans between the initial zoonotic event and the acquisition of the polybasic cleavage site. Sufficient opportunity could have arisen if there had been many prior zoonotic events that produced short chains of human-to-human transmission over an extended period.
Sure this would be plausible… other than the fact that, as we cover in our report, that statistical analysis shows that this thing didn’t hit humans until November of 2019, which this article agrees with. But zoonotic jumps only occur after a genomic trial-and-error process where the virus jumps to one host, spreads to a few new hosts, and then fizzles out. There is absolutely no evidence anywhere of this occurring. Every single data points to this thing hitting humans in November and being immediately adapted and dangerous. There is no trace whatsoever of it creating small clusters of infections and dying out – stating there could have been doesn’t mean it’s been seen. It hasn’t. And as our report covers, this would require sustained interaction with the intermediate host – how does that happen in the middle of a massive modern urban metropolis the size of NYC? And where is this intermediate host anyways? If an intermediate host isn’t needed, is it some magical sleep-flying bat that decided not to hibernate and fight crime in Wuhan when it’s buddies were all hibernating, creating the sustained interactions with humans as it fought for Justice? Because that’s about as plausible as what’s being proposed here.
The presence in pangolins of an RBD very similar to that of SARS-CoV-2 means that we can infer this was also probably in the virus that jumped to humans.
Again, analysis of the neutral sites shows that pangolins were almost certainly not in play.
Furthermore, a hypothetical generation of SARS-CoV-2 by cell culture or animal passage would have required prior isolation of a progenitor virus with very high genetic similarity, which has not been described
This means nothing. There is no open-source shared database of viruses. No one has any idea what viruses are in China’s BSL-4 lab, where they’ve been collecting these viruses for years. As mentioned, one of our persons-of-interest was the very first person to isolate a coronavirus from a bat that uses the ACE2 receptor. He also worked at UNC in Baric’s lab making the hyper-virulent bat coronavirus in 2015.
Subsequent generation of a polybasic cleavage site would have then required repeated passage in cell culture or animals with ACE2 receptors similar to those of humans, but such work has also not previously been described.
The fuck it hasn’t.
Retrospective serological studies could also be informative, and a few such studies have been conducted showing low-level exposures to SARS-CoV-like coronaviruses in certain areas of China26. Further serological studies should be conducted to determine the extent of prior human exposure to SARS-CoV-2.
Beyond the statistical analysis that indicates it only hit humans in November in 2019, is the fact that the version of COVID-19 found in the first few dozen hosts was exactly the same – there aren’t any variants whatsoever, just one version. This is not what would be found with the genomic trial-and-error of a full zoonotic jump, which requires sustained human-to-human transmission as different variants of the virus try and fail to adapt to human biology. Here, only one variant was found in all the initial infected humans, instead of the multiple variants that would be expected. But does fit what would happen if a virus that already had high affinity to the ACE2 receptor, which is the same in human and ferrets, leaked out of a lab. But addressing this point in particular, oh weird, the study they cite from March of 2018 was done mostly on people who live in villages barely a kilometer away from bat caves. A far cry from a massive urban city bout the size of NYC. Oh, and how many of these villagers, who live about a kilometer or less from bat caves, had antibodies indicating exposure to bat coronaviruses? Two-point-seven percent. (There is hand-waving about how long antibodies persist in humans, but I’m pretty sure it’s more than long enough.) That study actually sampled people living in Wuhan too and found… no evidence whatsoever of exposure to “SARS-CoV-like coronaviruses.” So are these peer-reviewers just straight chugging lead paint, or are they on the take too?
The finding of SARS-CoV-like coronaviruses from pangolins with nearly identical RBDs, however, provides a much stronger and more parsimonious explanation of how SARS-CoV-2 acquired these via recombination or mutation1
Again, just demonstrably false.
Get the real story here.
TRANSCRIPT: Bioweapons Expert Dr. Francis Boyle On Coronavirus
By
GreatGameIndia -
February 5, 2020 | Last modified on March 16th, 2020 at 11:02 pm,
A recent interview with Bioweapons expert Dr. Francis Boyle published by GreatGameIndia and conducted by Geopolitics & Empire, has been exploding across the world the past few days as the truth is emerging on the origins of the Coronavirus Bioweapon.
Francis Boyle is a professor of international law at the University of Illinois College of Law. He drafted the U.S. domestic implementing legislation for the Biological Weapons Convention, known as the Biological Weapons Anti-Terrorism Act of 1989, that was approved unanimously by both Houses of the U.S. Congress and signed into law by President George H.W. Bush.
In the exclusive interview, Dr. Boyle touches upon GreatGameIndia‘s exclusive report Coronavirus Bioweapon – where we reported in detail how Chinese Biowarfare agents working at the Canadian lab in Winnipeg were involved in the smuggling of Coronavirus to Wuhan’s lab from where it is believed to have been leaked.
In this bombshell interview (full transcript below), Boyle talks about:
The bioweapons origins of the coronavirus
How the Deep State deployed anthrax on US soil to whip up publicity about biological weapons and increase funding for bioweapons labs
Why the WHO and CDC are both criminal organizations which are complicit in the covert development of biological weapons
The “death science” industry and why the US government has spent over $100 billion developing self-replicating weapons
Details about the Pirbright Institute and its ties to bioweapons, depopulation, vaccines and coronavirus patents. (It’s partially funded by Bill & Melinda Gates)
Why all BSL-3 and BSL-4 labs in the world should be banned and shut down.
Full transcript
Geopolitics and Empire: Geopolitics & Empire is joined by Dr. Francis Boyle, who is international law professor at the University of Illinois. We’ll be discussing the Wuhan coronavirus and biological warfare. He’s served as counsel to numerous governments such as Bosnia and Herzegovina and the Palestinian authority. He’s represented numerous national international bodies in the areas of human rights, war crimes and genocide, nuclear policy, and biowarfare. He’s written numerous books, one of my favorites being “Destroying Libya and World Order”, which I assigned as mandatory reading material for my own students when I taught at the Monterrey Institute of Technology.
But most important for this interview, he’s written a book called “Biowarfare and Terrorism”, and drafted the US domestic implementing legislation for the biological weapons convention, known as the Biological Weapons Anti-Terrorism Act of 1989 that was approved unanimously by both houses of the US Congress and signed into law by President Bush. Thanks for joining us, Dr. Boyle.
Dr. Francis Boyle: Wow. Thank you so much for having me on and thanks for that kind introduction.
Geopolitics and Empire: Now let’s get to what’s been on the news recently. This coronavirus in Wuhan. There have been some reports recently, there’s a really interesting website called GreatGameIndia that has been reporting on this. They’ve been talking about China, which they say has been complying with biological weapons convention in recent years.
But then there are some people in the US and experts that have been saying that in reality, China isn’t complying with the weapons convention. And I think neither, perhaps the US as well. I’m wondering if China is developing its own biosafety level four lab in Wuhan and elsewhere, as you know, as a type of deterrence. Is it a type of a biological arms race that we have going on?
You told me in an email that you suspect China was developing the coronavirus as a dual use of biowarfare weapons agent. Also, what do you make of reports that Chinese scientists have been stealing research and viruses, including the coronavirus from a Canadian bio lab this past December?
And as well, Chinese nationals have been charged with smuggling vials of biological research to China from the US with the aid of Charles Lieber who was the chair of Harvard’s chemistry department. And he also happens to be in 2011 a strategic scientist at Wuhan University. So, can you tell us what’s going on with this recent outbreak in Wuhan?
Dr. Francis Boyle: Well, that’s a lot of questions. I guess we can take them one at a time, but if you just do a very simple Google search on “Does China have a BSL-4 laboratory?”, Wuhan comes up right away. It’s at the top of the list. That’s all with the moment this type of thing happened I began to do that. So a BSL-4 is the most serious type. And basically BSL-4 labs, we have many of them here in the United States, are used to develop offensive biological warfare weapons with DNA genetic engineering.
So it does seem to me that the Wuhan BSL-4 is the source of the coronavirus. My guess is that they were researching SARS, and they weaponize it further by giving it a gain of function properties, which means it could be more lethal.
Indeed, the latest report now is it’s a 15% fatality rate, which is more than SARS at 83% infection rate. A typical gain of function travels in the air so it could reach out maybe six feet or more from someone emitting a sneeze or a cough. Likewise, this is a specially designated WHO research lab. The WHO was in on it and they knew full well what was going on there.
Yes. It’s also been reported that Chinese scientists stole coronavirus materials from the Canadian lab at Winnipeg. Winnipeg is Canada’s formal center for research, developing, testing, biological warfare weapons. It’s along the lines of Fort Detrick here in the United States of America. I have three degrees from Harvard. It would not surprise me if something was being stolen out of Harvard to turn over to China. I read that report. I don’t know what was in those vials one way or the other.
But the bottom line is I drafted the US domestic implementing legislation for the Biological Weapons Convention that was approved unanimously by both Houses in the United States Congress signed into law by President Bush Sr. that it appears the coronavirus that we’re dealing with here is an offensive biological warfare weapon that leaped out of Wuhan BSL-4. I’m not saying it was done deliberately. But there had been previous reports of problems with that lab and things leaking out of it. I’m afraid that is what we are dealing with today.
Geopolitics and Empire: We’ll be talking about the Wuhan and the coronavirus and China, but can you give us kind of like a bigger context. I know you’ve, previously, in interviews said that since 9/11, you think that the US has spent $100 billion on biological warfare research. We know the Soviet Union, if I’m not mistaken, developed anthrax as a bioweapon. And you’ve also mentioned that UK, France, Israel and China are all involved in biological warfare weapons research.
And something interesting, I believe one or two years ago a Bulgarian journalist and the Russian government shared their concern of the discovery of a US bioweapons lab in the country of Georgia. You’ve commented how in Africa, US has set up bioweapons labs to work on Ebola, which I think is illegal under international law. But they were allowed somehow to put those in Africa. Can you give us like a bigger picture? What’s going on with these different countries and what’s the purpose of this research?
Dr. Francis Boyle: All these BSL-4 labs are by United States, Europe, Russia, China, Israel are all there to research, develop, test biological warfare agents. There’s really no legitimate scientific reason to have BSL-4 labs. That figure I gave $100 billion, that was about 2015 I believe. I had crunched the numbers and came up with that figure the United States since 9/11.
To give you an idea that’s as much in constant dollars as the US spent to develop the Manhattan Project and the atom bomb. So it’s clearly all weapons related. We have well over 13,000 alleged life science scientists involved in research developed testing biological weapons here in the United States. Actually this goes back it even precedes 9/11 2001.
I have another book, The Future of International Law and American Foreign Policy, tracing that all the way back to the Reagan administration under the influence of the neocons and they got very heavily involved in research development testing of biological weapons with DNA genetic engineers. It was because of that I issued my plea in 1985 in a Congressional briefing sponsored by the Council for Responsible Genetics, I’m a lawyer for them. They’re headquartered in Cambridge, Mass. All the MIT, Harvard people are involved in that, the principal ones. And then they asked me to draft the implementing legislation.
The implementing legislation that I drafted was originally designed to stop this type of work. “Death science work”, I call it, “by the United States government”. After 9/11, 2001, it just completely accelerated. My current figure, that last figure a 100 billion. I haven’t had a chance to re-crunch the numbers because I just started classes. But you have to add in about another 5 billion per year.
Basically, this is offensive biological weapons raised by the United States government and with its assistance in Canada and Britain. And so other States, the world have responded accordingly including Russia and China. They were going to set up a whole series of BSL-4 facilities as well. And you know Wuhan was the first. It backfired on them.
Geopolitics and Empire: Would you basically consider what happened and Wuhan and just boil it down to ineptitude or incompetence on the Chinese part?
Dr. Francis Boyle: Well, it’s criminality. It does appear they stole something there from Winnipeg. This activity that they engaged in clearly violates the Biological Weapons Convention. Research development of biological weapons these days is an international crime, the use of it would be. That was criminal.
I’m not saying they deliberately inflicted this on their own people, but it leaked out of there and all these BSL-4 facilities leak. Everyone knows that who studies this. So this was a catastrophe waiting to happen. Unfortunately, it happened. The Chinese government under Xi and his comrades there have been covering this up from the get-go. The first reported case was December 1, so they’d been sitting on this until they couldn’t anymore. And everything they’re telling you is a lie. It’s propaganda.
The WHO still refuses to declare a global health emergency. It said Tedros was over there shaking hands with Xi and smiling and yanking it up. The WHO was in on it. They’ve approved many of these BSL-4 labs., they know exactly what’s going on and that is a WHO research-approved laboratory. They know what’s going on too. You can’t really believe anything the WHO is telling you about this, either they’re up to their eyeballs in it, in my opinion.
Geopolitics and Empire: I’d probably agree with you that this outbreak in Wuhan was an accidental leak from the laboratory. But just your thoughts, it’s happening at quite an opportune time because namely we’re smack in the middle of a US-China new Cold War, which is currently characterized by economic warfare such as the trade war among other forms of hybrid and technological warfare. And it seems the Wuhan outbreak will likely hit the Chinese economy hard. The Chinese are flat out dismissing any idea that the US is involved in. Like I said, it’s probably they made the mistakes in the Wuhan lab. What are your thoughts of any seemingly, this would benefit the US…
Dr. Francis Boyle: When the outbreak occurred, of course I considered that alternative too. When you have an outbreak, you’re never quite sure who or what is behind it. It certainly isn’t bats, that’s ridiculous. They made the same argument on Ebola in West Africa. I demolished that online. You can check it out. So I kept competing theories about this.
But right now, when you originally contacted me, I said I wasn’t prepared to comment because I was weighing the evidence. I’m a law professor and a lawyer, I try to do the best I can to weigh the evidence. But right now, the Wuhan BSL-4 in my opinion is the most likely source, apply Occam’s razor, the simplest explanation. I’m not ruling out some type of sabotage. But right now, I believe that is the source here.
Geopolitics and Empire: And you mentioned WHO. I’d like to just get your thoughts on the WHO and the Big Pharma. There’s also some analysts who are downplaying this news media hype of the coronavirus. You’ve just said that it seems to be lethal, but if we go back a decade to the 2009 swine flu, which I believe didn’t have too many casualties, but I think profited greatly the pharmaceutical companies. If I recall that back in 2009, many countries purchased great stocks of the vaccines and they ended up not using anywhere from 50 to 80% of the vaccines that they purchased.
You’ve previously stated in an interview that the World Health Organization is a front for Big Pharma if I’m not mistaken. Robert F. Kennedy Jr. also agrees and he says, you know, 50% of WHO funding comes from pharmaceutical companies. And that the CDC itself is also severely compromised. What are your thoughts on the WHO? The CDC?
Dr. Francis Boyle: Can’t trust anything the WHO says because they’re all bought and paid for by Big Pharma and when they work in cahoots with the CDC, which is the United States government, they work in cahoots with Fort Detrick, so you can’t trust any of it.
However, the swine flu and yes, I agree pharma made a lot of money, but that swine flu which I looked at it, it did seem to me to be a genetically modified biological warfare weapon. It was a chimera of three different types of genetic strains that someone put it together in a cocktail. Fortunately, it was not as lethal as all of us fear. So fine. But as I said, this figure I just gave to you was Saturday from Lancet, which is a medical publication, saying it’s a 15% fatality rate and an 83% infection rate. So it’s quite serious, I think, far more serious than the swine flu.
As for big pharma, sure they’re all trying to profit off this today as we speak. There was a big article yesterday in the Wall Street Journal, all big pharma trying to peddle whatever they can over there in China even if it’s worthless and won’t help. We do know, if you read the mainstream news media they say there isn’t a vaccine.
Well, there is, it’s by the Pirbright Institute in Britain that’s tied into their biological warfare program over there. They were behind the hoof and mouth disease outbreak over there that wiped out their cattle herd and it leaked out of there. So it’s clear they’re working on a hoof and mouth biological warfare weapon, but the vaccine is there. I have the patent for it here, I haven’t had a chance to read the patent it’s about 25 pages long and my classes just resume. So eventually, I get some free time and I’ll read the patent.
You can’t patent a vaccine with the United States patent office unless the science is there. So there is a vaccine. Everyone’s lying about that, no one’s pointing this out – there’s a vaccine but instead big pharma wants to make money and the researchers say, well, it’ll take three months and we’re racing forward, you know. Everyone’s gonna make a buck off of this, that’s for sure. But there is a vaccine, I have the patent here. It’s been patented by the United States government.
So obviously, I don’t know exactly how workable it is, but it’s a vaccine. I don’t know why it isn’t out there now? Why isn’t someone saying there is a vaccine? Perhaps political leaders have already been vaccinated for all I know, I really don’t know. But there is a vaccine, Pirbright is well known there in Britain and it’s tied into Fort Detrick and CDC is tied into Fort Detrick too. So they all know there’s a patented vaccine.
Geopolitics and Empire: And just to get your comment on, I mean, something to related to this, which was my next question. So I think, I’m not sure if it’s that same Institute that you just mentioned that has the patent. I read somewhere that the Bill & Melinda Gates foundation maybe funds or has some connection to that Institute that has the patent.
Dr. Francis Boyle: I think they do. The Bill & Melinda Gates information, they fund this type of DNA genetically engineered biological warfare work. That’s correct. So you can’t trust anything they’re telling you that somehow they’re out there trying to make the world a better place. I mean, we have Bill Gates publicly admitting that the world be a better place if there were a lot less people. So the Bill & Melinda Gates foundation, they are wolves in sheep’s clothing and they are funding this type of stuff. Sure.
Geopolitics and Empire: And just your comment, there was also the report that I guess it was a consortium of companies which included the Gates foundation that back in just two or three months ago in October of 2019 they held a pandemic exercise simulating an outbreak. I mean, what are the chances specifically of a coronavirus and it was called events 201. People can find this online online and they gave a list of seven recommendations for governments and international organizations to take. I also find that kind of interesting how they had this simulation.
Dr. Francis Boyle: That’s correct. It raises that question, the origins of what happened here. But right now, I’m just looking at the evidence I have and applying Occam’s razor and we know that Wuhan BSL-4 was research developing, testing, SARS as a biological warfare agent. So it could have been, they gave it this DNA genetic engineering enhanced properties gain of function which we do here in the West, in the United States all the time. We have all sorts of research that is clearly a bio warfare research that has been approved by the National Institutes of Health, it’s a joke. They know full well they are proving all kinds of biological warfare research and it gets funded by the United States government.
Geopolitics and Empire: And you’ve also mentioned in the email to me that what happened in the biosafety lab level 4 in Wuhan calls into question the safety of all of these level 3and 4four labs around the world.
Dr. Francis Boyle: They’re complete unsafe. BSL-3 and BSL-4 lab are only designed for research development testing of offense of biological warfare agents. In my opinion, they serve no legitimate purpose at all. They should all be shut down, every one of them. Even assuming, they’re simply too dangerous. If you want, there’s an excellent documentary called Anthrax Wars by Nadler and Coen and I’m in there. Repeatedly at the end, I say with respect to these labs, three and four, this is a catastrophe waiting to happen. Well, I’m afraid the catastrophe is now happened. So there it is.
Geopolitics and Empire: Yeah, I was just watching that documentary before we connected and I recommend the listeners go check that out. Do you see, in the future, any countries, if we come to a conflict between US, EU, Israel, Saudi Arabia, Iran, China, Russia, I mean you name it. Do you see any of these countries actually utilizing these biological weapons? I mean, it’s illegal under international law but we know like in the past that international law isn’t followed. Do you think that there’s a real danger of this escalating?
Dr. Francis Boyle: For sure. That’s the only reason they develop these biological weapons to eventually be used, sure. I mean, it’s like the Manhattan project, we put all that money into developing an atom bomb and even though it was not needed to end world war II they still knew Hiroshima and Nagasaki. So, yes, I think that’s correct. And also these can be used covertly. Anytime you see an unexplained sudden outbreak of a disease like this anywhere in the world, both for human beings and or animals, I always suspect the bio warfare agent is at work. I monitor the situation like I did at Wuhan until I can reach a conclusion. Yes, they can be used as the eyes for the United States government, today they are fully prepared, armed, equipped, supplied to wage a biological warfare with anthrax.
These other more exotic things I don’t know, but they have the weapons, there are stockpiles. We have to understand if you read Seymour Martin Hersh’s book published about 1968, he won the Pulitzer prize, he had the whole offensive US biological warfare industry in there back before it was illegal and criminal. Basically after 9/11, 2001, that entire industry – offensive biological warfare industry has been reconstituted here in the United States with all these BSL-4 BSL-3 labs, well over 13,000, alleged scientists sort of like Dr. Mengele working on these things. Other countries have responded in kind like Russia, like China, France is involved, Britain’s involved. Sure.
Geopolitics and Empire: I just wanted to get your thoughts on, in the last few years there was the Russian double agent spy Sergei Skripal who had been allegedly poisoned with Novichok out in Britain and I thought it was funny. It just so happened where he was allegedly poisoned, he was right in Porton down the British bio weapons lab, I guess the world’s first bio weapons lab that was created in 1916. I mean, I don’t know if you have thoughts on that whole incident.
Dr. Francis Boyle: Yeah, I was right down the street from Porton Down, so applying Occam’s razor who you think might’ve been behind this and it was not a nerve agent. A nerve agent would have killed him immediately. This is Novichok. It was something else like DX or something like that. So fine. But, I would just say that I don’t think that was a coincidence, but, you know, there you go. There’s the, obviously there’s a lot of speculation on that.
Geopolitics and Empire: Something else that’s kind of interesting. You’ve written in bio warfare and terrorism in your book and there’s also Graeme Macqueen, I think your colleague who wrote the anthrax deception the case for domestic conspiracy…
Dr. Francis Boyle: Everything you said in there. That’s correct.
Geopolitics and Empire: I’m wondering also if this new war for biotechnological dominance, whatever you want to call it, if it can also be used kind of as a pretext for the centralization of political power and the initiation of wars like I guess it did in the 2003 Iraq war. I mean, is this another danger that we get these events like now this coronavirus and then governments will call for a centralization of greater power and taking away some of our civil liberties?
Dr. Francis Boyle: Sure. If you look at the October, 2001 anthrax attacks here in the United States, that was clearly by elements of the United States government that was behind that. That was a super weapons grade anthrax with a trillion spores per gram and it floated in the air solely a very sophisticated biological weapons lab like Fort Detrick could produce that. And they use that anthrax attack including on Congress to brand through the USA Patriot act which basically turned the United States to a police state which is what we have now. You have to understand the Pentagon, Fort Dietrich made the dugway proving ground still has a stockpile of that super weapons grade anthrax that we saw in October of 2001 that they can use the next time they want to do something like that to further develop the American police thing. Right.
Geopolitics and Empire: Is there anything else you feel important to mention regarding this Wuhan Coronavirus outbreak or biological warfare or any other thoughts you’d like to leave us with?
Dr. Francis Boyle: Well, you just can’t believe anything the Chinese government, the WHO, the CDC are telling. They’re all lies because they know what’s going on here and so you’re going to have to figure it out as fast as you can. But in my opinion, as of this time and I’m fully prepared to consider further evidence on this, it does seem to me that this was a DNA genetically engineered biological warfare agent leaking out of Wuhan that has gain-of-function properties which can make it more lethal. I think they are probably doing something with SARS to make it a lot more lethal and more infectious. And so for that reason, you have to take extreme precautions and they’re now finally admitted anyone within six feet can be infected, whereas with SARS that was about two feet. Well, that’s gaining a function right there and that should be a tip off.
So, I guess you’re gonna have to protect yourself. Laurie Garrett had a pretty good essay in a foreign policy yesterday and she was over there covering the SARS and she has very good advice in there except that she took the SARS figure out two to three feet and said well, you gotta stay to two to three. I think you’ve got to stay at least six feet away because this is gained function. It can flow through the air and infect and it can get you in the eyes. Any orifice, the mouth, maybe the ears, we’re not sure at this point.
Geopolitics and Empire: I’m here on the border of China in Kazakhstan and I was just reading yesterday – today that they’re no longer allowing Chinese citizens into Kazakhstan without a medical paper, a medical check to get their visas to enter Kazakhstan
Dr. Francis Boyle: Those medical checks are worthless because this is just public relations by all the governments involved because there is a 14 day incubation period where people can still be infected. So someone could walk right through a medical inspection and passing a gate into your country and then they come down with the coronavirus. So that’s all public relations in my opinion by governments and they know it and they’re just sending people out there with temperatures and things like that. It’s not like SARS, this is more dangerous than SARS. As I said, I think that Wuhan lab, we know they had SARS in there that they were dealing with and I think they enhanced it at and I’m afraid that’s what we’re dealing with. But you know, I’m keeping an open mind as to what other sources that might have and I wasn’t prepared to say anything until that Wuhan lab is right there and it’s dealing with coronavirus. So again, apply Occam’s razor. It seems to me that’s the simplest explanation here.
Geopolitics and Empire: I guess my, one of my final question would be in the months ahead, apart of what you say staying six feet away from people. I’ve read taking high doses of vitamin C and other things like this can help you. But, if they come out as the situation develops and if it gets worse and they come out with a coronavirus vaccine, should people take it or not? What are your thoughts?
Dr. Francis Boyle: Well, what I would say is this. Right now, if you look at the article at the Wall Street Journal, big pharma is trying to sell all sorts of – they’re taking all their drugs off the shelf and say well let’s see if it works. Which is preposterous. Okay. The scientists are saying, well, we can get you a vaccine maybe two to three months but they’re not tested. So what we do know, however, is that Pirbright vaccine has been patented. So all I can assume is that that might work. But I don’t think I’d be taking any of these other vaccines. No, you have no idea what’s in there. You’ll be the Guinea pig for big pharma and everyone figures they’re gonna make a lot of money here. So I’ll keep my eye open on this and how it develop but I wouldn’t trust anything they’re trying to sell right now. They’re just pulling these things off the shelf.
If they do come up with something in two to three months, even that’s not going to be tested in accordance with normal scientific protocol. So it’s going to be a crap shoot. If it’s going to help you, indeed it might not help you because they’ll be using for this vaccines (these DNA genetic engineered vaccines) they’ll be using live coronavirus probably and sticking it in there and giving you some live coronavirus on the theory you’ll develop an immunity. That’s the way a lot of these vaccines worked out, that’s what happened with the Ebola vaccine that created the Ebola pandemic there in West Africa. They were testing out a vaccine on poor black Africans, as usual, and this vaccine had live Ebola in it so it gave them Ebola. So again, I’d be very careful even if they do come up with these vaccines two to three months from now, very careful. Why would you want to inject the live coronavirus in you?
Geopolitics and Empire: All right. I don’t believe you have a strong online presence. How can people best follow your work? I suppose to search for interviews as well as get your books.
Dr. Francis Boyle: Well, basically I’m blackballed and blacklisted off all the mainstream news media here on purpose. As far as I can figure out, the US government gave an order that I should not be interviewed by anyone, so I’m not. I guess you could just put my name in there under Google, Google alert, and some interviews might come up. What happened was, right after the anthrax attacks of 9/11 2001, I was giving a lecture out at Harvard m Alma Mater. I was running a panel on biological warfare for the council for responsible genetics and it was at Harvard Divinity School and as I was going in, there was a Fox camera crew there from Boston and I said it looks to me like this has come out of the US government lab. We know they do research and testing on anthrax. Then I said the same thing there at Harvard then I gave an interview to a radio station in Washington, D C then I gave an interview on that to the BBC. So the whole world saw it and at that point I was completely cut off and I’ve been cut off ever since. So you probably not going to hear too many interviews from me here. As for my book. Biowarfare & Terrorism, you can just get it at amazon.com. That picks up the story pretty much from 9/11 2001 and until it went to press and then there are interviews I’d given to an investigative reporter, Sherwood Ross and a big one I just sent you and you might want to put that on your web page. That was pretty comprehensive.
Geopolitics and Empire: Yeah, I read that as well and I’ll include the link in the description of this interview so people can go check that out. You’re not the only academic I know and have heard of others that similar things have happened and that’s just I guess the price we pay for telling the truth. Again, for listeners, if people wanted to have a broader context and deeper understanding of what’s happening today especially with biological warfare as well as us foreign policy and international affairs, I urge you to get Dr. Francis Boyle’s books and listen to his interviews as well as his colleagues book. Graeme Macqueen, The Anthrax Deception, The Case For Domestic Conspiracy. Thank you for being with us, Dr. Boyle.
Dr. Francis Boyle: Well, thank you and again, please understand these are my current opinions. I could change my opinion here based on more evidence. So I’m just looking at the evidence out there as I see it and you have to understand there is so much disinformation, lies and propaganda that it’s kind of very difficult to distinguish truth from fact. I’m doing the best job I can here.
GreatGameIndia -
February 5, 2020 | Last modified on March 16th, 2020 at 11:02 pm,
A recent interview with Bioweapons expert Dr. Francis Boyle published by GreatGameIndia and conducted by Geopolitics & Empire, has been exploding across the world the past few days as the truth is emerging on the origins of the Coronavirus Bioweapon.
Francis Boyle is a professor of international law at the University of Illinois College of Law. He drafted the U.S. domestic implementing legislation for the Biological Weapons Convention, known as the Biological Weapons Anti-Terrorism Act of 1989, that was approved unanimously by both Houses of the U.S. Congress and signed into law by President George H.W. Bush.
In the exclusive interview, Dr. Boyle touches upon GreatGameIndia‘s exclusive report Coronavirus Bioweapon – where we reported in detail how Chinese Biowarfare agents working at the Canadian lab in Winnipeg were involved in the smuggling of Coronavirus to Wuhan’s lab from where it is believed to have been leaked.
In this bombshell interview (full transcript below), Boyle talks about:
The bioweapons origins of the coronavirus
How the Deep State deployed anthrax on US soil to whip up publicity about biological weapons and increase funding for bioweapons labs
Why the WHO and CDC are both criminal organizations which are complicit in the covert development of biological weapons
The “death science” industry and why the US government has spent over $100 billion developing self-replicating weapons
Details about the Pirbright Institute and its ties to bioweapons, depopulation, vaccines and coronavirus patents. (It’s partially funded by Bill & Melinda Gates)
Why all BSL-3 and BSL-4 labs in the world should be banned and shut down.
Full transcript
Geopolitics and Empire: Geopolitics & Empire is joined by Dr. Francis Boyle, who is international law professor at the University of Illinois. We’ll be discussing the Wuhan coronavirus and biological warfare. He’s served as counsel to numerous governments such as Bosnia and Herzegovina and the Palestinian authority. He’s represented numerous national international bodies in the areas of human rights, war crimes and genocide, nuclear policy, and biowarfare. He’s written numerous books, one of my favorites being “Destroying Libya and World Order”, which I assigned as mandatory reading material for my own students when I taught at the Monterrey Institute of Technology.
But most important for this interview, he’s written a book called “Biowarfare and Terrorism”, and drafted the US domestic implementing legislation for the biological weapons convention, known as the Biological Weapons Anti-Terrorism Act of 1989 that was approved unanimously by both houses of the US Congress and signed into law by President Bush. Thanks for joining us, Dr. Boyle.
Dr. Francis Boyle: Wow. Thank you so much for having me on and thanks for that kind introduction.
Geopolitics and Empire: Now let’s get to what’s been on the news recently. This coronavirus in Wuhan. There have been some reports recently, there’s a really interesting website called GreatGameIndia that has been reporting on this. They’ve been talking about China, which they say has been complying with biological weapons convention in recent years.
But then there are some people in the US and experts that have been saying that in reality, China isn’t complying with the weapons convention. And I think neither, perhaps the US as well. I’m wondering if China is developing its own biosafety level four lab in Wuhan and elsewhere, as you know, as a type of deterrence. Is it a type of a biological arms race that we have going on?
You told me in an email that you suspect China was developing the coronavirus as a dual use of biowarfare weapons agent. Also, what do you make of reports that Chinese scientists have been stealing research and viruses, including the coronavirus from a Canadian bio lab this past December?
And as well, Chinese nationals have been charged with smuggling vials of biological research to China from the US with the aid of Charles Lieber who was the chair of Harvard’s chemistry department. And he also happens to be in 2011 a strategic scientist at Wuhan University. So, can you tell us what’s going on with this recent outbreak in Wuhan?
Dr. Francis Boyle: Well, that’s a lot of questions. I guess we can take them one at a time, but if you just do a very simple Google search on “Does China have a BSL-4 laboratory?”, Wuhan comes up right away. It’s at the top of the list. That’s all with the moment this type of thing happened I began to do that. So a BSL-4 is the most serious type. And basically BSL-4 labs, we have many of them here in the United States, are used to develop offensive biological warfare weapons with DNA genetic engineering.
So it does seem to me that the Wuhan BSL-4 is the source of the coronavirus. My guess is that they were researching SARS, and they weaponize it further by giving it a gain of function properties, which means it could be more lethal.
Indeed, the latest report now is it’s a 15% fatality rate, which is more than SARS at 83% infection rate. A typical gain of function travels in the air so it could reach out maybe six feet or more from someone emitting a sneeze or a cough. Likewise, this is a specially designated WHO research lab. The WHO was in on it and they knew full well what was going on there.
Yes. It’s also been reported that Chinese scientists stole coronavirus materials from the Canadian lab at Winnipeg. Winnipeg is Canada’s formal center for research, developing, testing, biological warfare weapons. It’s along the lines of Fort Detrick here in the United States of America. I have three degrees from Harvard. It would not surprise me if something was being stolen out of Harvard to turn over to China. I read that report. I don’t know what was in those vials one way or the other.
But the bottom line is I drafted the US domestic implementing legislation for the Biological Weapons Convention that was approved unanimously by both Houses in the United States Congress signed into law by President Bush Sr. that it appears the coronavirus that we’re dealing with here is an offensive biological warfare weapon that leaped out of Wuhan BSL-4. I’m not saying it was done deliberately. But there had been previous reports of problems with that lab and things leaking out of it. I’m afraid that is what we are dealing with today.
Geopolitics and Empire: We’ll be talking about the Wuhan and the coronavirus and China, but can you give us kind of like a bigger context. I know you’ve, previously, in interviews said that since 9/11, you think that the US has spent $100 billion on biological warfare research. We know the Soviet Union, if I’m not mistaken, developed anthrax as a bioweapon. And you’ve also mentioned that UK, France, Israel and China are all involved in biological warfare weapons research.
And something interesting, I believe one or two years ago a Bulgarian journalist and the Russian government shared their concern of the discovery of a US bioweapons lab in the country of Georgia. You’ve commented how in Africa, US has set up bioweapons labs to work on Ebola, which I think is illegal under international law. But they were allowed somehow to put those in Africa. Can you give us like a bigger picture? What’s going on with these different countries and what’s the purpose of this research?
Dr. Francis Boyle: All these BSL-4 labs are by United States, Europe, Russia, China, Israel are all there to research, develop, test biological warfare agents. There’s really no legitimate scientific reason to have BSL-4 labs. That figure I gave $100 billion, that was about 2015 I believe. I had crunched the numbers and came up with that figure the United States since 9/11.
To give you an idea that’s as much in constant dollars as the US spent to develop the Manhattan Project and the atom bomb. So it’s clearly all weapons related. We have well over 13,000 alleged life science scientists involved in research developed testing biological weapons here in the United States. Actually this goes back it even precedes 9/11 2001.
I have another book, The Future of International Law and American Foreign Policy, tracing that all the way back to the Reagan administration under the influence of the neocons and they got very heavily involved in research development testing of biological weapons with DNA genetic engineers. It was because of that I issued my plea in 1985 in a Congressional briefing sponsored by the Council for Responsible Genetics, I’m a lawyer for them. They’re headquartered in Cambridge, Mass. All the MIT, Harvard people are involved in that, the principal ones. And then they asked me to draft the implementing legislation.
The implementing legislation that I drafted was originally designed to stop this type of work. “Death science work”, I call it, “by the United States government”. After 9/11, 2001, it just completely accelerated. My current figure, that last figure a 100 billion. I haven’t had a chance to re-crunch the numbers because I just started classes. But you have to add in about another 5 billion per year.
Basically, this is offensive biological weapons raised by the United States government and with its assistance in Canada and Britain. And so other States, the world have responded accordingly including Russia and China. They were going to set up a whole series of BSL-4 facilities as well. And you know Wuhan was the first. It backfired on them.
Geopolitics and Empire: Would you basically consider what happened and Wuhan and just boil it down to ineptitude or incompetence on the Chinese part?
Dr. Francis Boyle: Well, it’s criminality. It does appear they stole something there from Winnipeg. This activity that they engaged in clearly violates the Biological Weapons Convention. Research development of biological weapons these days is an international crime, the use of it would be. That was criminal.
I’m not saying they deliberately inflicted this on their own people, but it leaked out of there and all these BSL-4 facilities leak. Everyone knows that who studies this. So this was a catastrophe waiting to happen. Unfortunately, it happened. The Chinese government under Xi and his comrades there have been covering this up from the get-go. The first reported case was December 1, so they’d been sitting on this until they couldn’t anymore. And everything they’re telling you is a lie. It’s propaganda.
The WHO still refuses to declare a global health emergency. It said Tedros was over there shaking hands with Xi and smiling and yanking it up. The WHO was in on it. They’ve approved many of these BSL-4 labs., they know exactly what’s going on and that is a WHO research-approved laboratory. They know what’s going on too. You can’t really believe anything the WHO is telling you about this, either they’re up to their eyeballs in it, in my opinion.
Geopolitics and Empire: I’d probably agree with you that this outbreak in Wuhan was an accidental leak from the laboratory. But just your thoughts, it’s happening at quite an opportune time because namely we’re smack in the middle of a US-China new Cold War, which is currently characterized by economic warfare such as the trade war among other forms of hybrid and technological warfare. And it seems the Wuhan outbreak will likely hit the Chinese economy hard. The Chinese are flat out dismissing any idea that the US is involved in. Like I said, it’s probably they made the mistakes in the Wuhan lab. What are your thoughts of any seemingly, this would benefit the US…
Dr. Francis Boyle: When the outbreak occurred, of course I considered that alternative too. When you have an outbreak, you’re never quite sure who or what is behind it. It certainly isn’t bats, that’s ridiculous. They made the same argument on Ebola in West Africa. I demolished that online. You can check it out. So I kept competing theories about this.
But right now, when you originally contacted me, I said I wasn’t prepared to comment because I was weighing the evidence. I’m a law professor and a lawyer, I try to do the best I can to weigh the evidence. But right now, the Wuhan BSL-4 in my opinion is the most likely source, apply Occam’s razor, the simplest explanation. I’m not ruling out some type of sabotage. But right now, I believe that is the source here.
Geopolitics and Empire: And you mentioned WHO. I’d like to just get your thoughts on the WHO and the Big Pharma. There’s also some analysts who are downplaying this news media hype of the coronavirus. You’ve just said that it seems to be lethal, but if we go back a decade to the 2009 swine flu, which I believe didn’t have too many casualties, but I think profited greatly the pharmaceutical companies. If I recall that back in 2009, many countries purchased great stocks of the vaccines and they ended up not using anywhere from 50 to 80% of the vaccines that they purchased.
You’ve previously stated in an interview that the World Health Organization is a front for Big Pharma if I’m not mistaken. Robert F. Kennedy Jr. also agrees and he says, you know, 50% of WHO funding comes from pharmaceutical companies. And that the CDC itself is also severely compromised. What are your thoughts on the WHO? The CDC?
Dr. Francis Boyle: Can’t trust anything the WHO says because they’re all bought and paid for by Big Pharma and when they work in cahoots with the CDC, which is the United States government, they work in cahoots with Fort Detrick, so you can’t trust any of it.
However, the swine flu and yes, I agree pharma made a lot of money, but that swine flu which I looked at it, it did seem to me to be a genetically modified biological warfare weapon. It was a chimera of three different types of genetic strains that someone put it together in a cocktail. Fortunately, it was not as lethal as all of us fear. So fine. But as I said, this figure I just gave to you was Saturday from Lancet, which is a medical publication, saying it’s a 15% fatality rate and an 83% infection rate. So it’s quite serious, I think, far more serious than the swine flu.
As for big pharma, sure they’re all trying to profit off this today as we speak. There was a big article yesterday in the Wall Street Journal, all big pharma trying to peddle whatever they can over there in China even if it’s worthless and won’t help. We do know, if you read the mainstream news media they say there isn’t a vaccine.
Well, there is, it’s by the Pirbright Institute in Britain that’s tied into their biological warfare program over there. They were behind the hoof and mouth disease outbreak over there that wiped out their cattle herd and it leaked out of there. So it’s clear they’re working on a hoof and mouth biological warfare weapon, but the vaccine is there. I have the patent for it here, I haven’t had a chance to read the patent it’s about 25 pages long and my classes just resume. So eventually, I get some free time and I’ll read the patent.
You can’t patent a vaccine with the United States patent office unless the science is there. So there is a vaccine. Everyone’s lying about that, no one’s pointing this out – there’s a vaccine but instead big pharma wants to make money and the researchers say, well, it’ll take three months and we’re racing forward, you know. Everyone’s gonna make a buck off of this, that’s for sure. But there is a vaccine, I have the patent here. It’s been patented by the United States government.
So obviously, I don’t know exactly how workable it is, but it’s a vaccine. I don’t know why it isn’t out there now? Why isn’t someone saying there is a vaccine? Perhaps political leaders have already been vaccinated for all I know, I really don’t know. But there is a vaccine, Pirbright is well known there in Britain and it’s tied into Fort Detrick and CDC is tied into Fort Detrick too. So they all know there’s a patented vaccine.
Geopolitics and Empire: And just to get your comment on, I mean, something to related to this, which was my next question. So I think, I’m not sure if it’s that same Institute that you just mentioned that has the patent. I read somewhere that the Bill & Melinda Gates foundation maybe funds or has some connection to that Institute that has the patent.
Dr. Francis Boyle: I think they do. The Bill & Melinda Gates information, they fund this type of DNA genetically engineered biological warfare work. That’s correct. So you can’t trust anything they’re telling you that somehow they’re out there trying to make the world a better place. I mean, we have Bill Gates publicly admitting that the world be a better place if there were a lot less people. So the Bill & Melinda Gates foundation, they are wolves in sheep’s clothing and they are funding this type of stuff. Sure.
Geopolitics and Empire: And just your comment, there was also the report that I guess it was a consortium of companies which included the Gates foundation that back in just two or three months ago in October of 2019 they held a pandemic exercise simulating an outbreak. I mean, what are the chances specifically of a coronavirus and it was called events 201. People can find this online online and they gave a list of seven recommendations for governments and international organizations to take. I also find that kind of interesting how they had this simulation.
Dr. Francis Boyle: That’s correct. It raises that question, the origins of what happened here. But right now, I’m just looking at the evidence I have and applying Occam’s razor and we know that Wuhan BSL-4 was research developing, testing, SARS as a biological warfare agent. So it could have been, they gave it this DNA genetic engineering enhanced properties gain of function which we do here in the West, in the United States all the time. We have all sorts of research that is clearly a bio warfare research that has been approved by the National Institutes of Health, it’s a joke. They know full well they are proving all kinds of biological warfare research and it gets funded by the United States government.
Geopolitics and Empire: And you’ve also mentioned in the email to me that what happened in the biosafety lab level 4 in Wuhan calls into question the safety of all of these level 3and 4four labs around the world.
Dr. Francis Boyle: They’re complete unsafe. BSL-3 and BSL-4 lab are only designed for research development testing of offense of biological warfare agents. In my opinion, they serve no legitimate purpose at all. They should all be shut down, every one of them. Even assuming, they’re simply too dangerous. If you want, there’s an excellent documentary called Anthrax Wars by Nadler and Coen and I’m in there. Repeatedly at the end, I say with respect to these labs, three and four, this is a catastrophe waiting to happen. Well, I’m afraid the catastrophe is now happened. So there it is.
Geopolitics and Empire: Yeah, I was just watching that documentary before we connected and I recommend the listeners go check that out. Do you see, in the future, any countries, if we come to a conflict between US, EU, Israel, Saudi Arabia, Iran, China, Russia, I mean you name it. Do you see any of these countries actually utilizing these biological weapons? I mean, it’s illegal under international law but we know like in the past that international law isn’t followed. Do you think that there’s a real danger of this escalating?
Dr. Francis Boyle: For sure. That’s the only reason they develop these biological weapons to eventually be used, sure. I mean, it’s like the Manhattan project, we put all that money into developing an atom bomb and even though it was not needed to end world war II they still knew Hiroshima and Nagasaki. So, yes, I think that’s correct. And also these can be used covertly. Anytime you see an unexplained sudden outbreak of a disease like this anywhere in the world, both for human beings and or animals, I always suspect the bio warfare agent is at work. I monitor the situation like I did at Wuhan until I can reach a conclusion. Yes, they can be used as the eyes for the United States government, today they are fully prepared, armed, equipped, supplied to wage a biological warfare with anthrax.
These other more exotic things I don’t know, but they have the weapons, there are stockpiles. We have to understand if you read Seymour Martin Hersh’s book published about 1968, he won the Pulitzer prize, he had the whole offensive US biological warfare industry in there back before it was illegal and criminal. Basically after 9/11, 2001, that entire industry – offensive biological warfare industry has been reconstituted here in the United States with all these BSL-4 BSL-3 labs, well over 13,000, alleged scientists sort of like Dr. Mengele working on these things. Other countries have responded in kind like Russia, like China, France is involved, Britain’s involved. Sure.
Geopolitics and Empire: I just wanted to get your thoughts on, in the last few years there was the Russian double agent spy Sergei Skripal who had been allegedly poisoned with Novichok out in Britain and I thought it was funny. It just so happened where he was allegedly poisoned, he was right in Porton down the British bio weapons lab, I guess the world’s first bio weapons lab that was created in 1916. I mean, I don’t know if you have thoughts on that whole incident.
Dr. Francis Boyle: Yeah, I was right down the street from Porton Down, so applying Occam’s razor who you think might’ve been behind this and it was not a nerve agent. A nerve agent would have killed him immediately. This is Novichok. It was something else like DX or something like that. So fine. But, I would just say that I don’t think that was a coincidence, but, you know, there you go. There’s the, obviously there’s a lot of speculation on that.
Geopolitics and Empire: Something else that’s kind of interesting. You’ve written in bio warfare and terrorism in your book and there’s also Graeme Macqueen, I think your colleague who wrote the anthrax deception the case for domestic conspiracy…
Dr. Francis Boyle: Everything you said in there. That’s correct.
Geopolitics and Empire: I’m wondering also if this new war for biotechnological dominance, whatever you want to call it, if it can also be used kind of as a pretext for the centralization of political power and the initiation of wars like I guess it did in the 2003 Iraq war. I mean, is this another danger that we get these events like now this coronavirus and then governments will call for a centralization of greater power and taking away some of our civil liberties?
Dr. Francis Boyle: Sure. If you look at the October, 2001 anthrax attacks here in the United States, that was clearly by elements of the United States government that was behind that. That was a super weapons grade anthrax with a trillion spores per gram and it floated in the air solely a very sophisticated biological weapons lab like Fort Detrick could produce that. And they use that anthrax attack including on Congress to brand through the USA Patriot act which basically turned the United States to a police state which is what we have now. You have to understand the Pentagon, Fort Dietrich made the dugway proving ground still has a stockpile of that super weapons grade anthrax that we saw in October of 2001 that they can use the next time they want to do something like that to further develop the American police thing. Right.
Geopolitics and Empire: Is there anything else you feel important to mention regarding this Wuhan Coronavirus outbreak or biological warfare or any other thoughts you’d like to leave us with?
Dr. Francis Boyle: Well, you just can’t believe anything the Chinese government, the WHO, the CDC are telling. They’re all lies because they know what’s going on here and so you’re going to have to figure it out as fast as you can. But in my opinion, as of this time and I’m fully prepared to consider further evidence on this, it does seem to me that this was a DNA genetically engineered biological warfare agent leaking out of Wuhan that has gain-of-function properties which can make it more lethal. I think they are probably doing something with SARS to make it a lot more lethal and more infectious. And so for that reason, you have to take extreme precautions and they’re now finally admitted anyone within six feet can be infected, whereas with SARS that was about two feet. Well, that’s gaining a function right there and that should be a tip off.
So, I guess you’re gonna have to protect yourself. Laurie Garrett had a pretty good essay in a foreign policy yesterday and she was over there covering the SARS and she has very good advice in there except that she took the SARS figure out two to three feet and said well, you gotta stay to two to three. I think you’ve got to stay at least six feet away because this is gained function. It can flow through the air and infect and it can get you in the eyes. Any orifice, the mouth, maybe the ears, we’re not sure at this point.
Geopolitics and Empire: I’m here on the border of China in Kazakhstan and I was just reading yesterday – today that they’re no longer allowing Chinese citizens into Kazakhstan without a medical paper, a medical check to get their visas to enter Kazakhstan
Dr. Francis Boyle: Those medical checks are worthless because this is just public relations by all the governments involved because there is a 14 day incubation period where people can still be infected. So someone could walk right through a medical inspection and passing a gate into your country and then they come down with the coronavirus. So that’s all public relations in my opinion by governments and they know it and they’re just sending people out there with temperatures and things like that. It’s not like SARS, this is more dangerous than SARS. As I said, I think that Wuhan lab, we know they had SARS in there that they were dealing with and I think they enhanced it at and I’m afraid that’s what we’re dealing with. But you know, I’m keeping an open mind as to what other sources that might have and I wasn’t prepared to say anything until that Wuhan lab is right there and it’s dealing with coronavirus. So again, apply Occam’s razor. It seems to me that’s the simplest explanation here.
Geopolitics and Empire: I guess my, one of my final question would be in the months ahead, apart of what you say staying six feet away from people. I’ve read taking high doses of vitamin C and other things like this can help you. But, if they come out as the situation develops and if it gets worse and they come out with a coronavirus vaccine, should people take it or not? What are your thoughts?
Dr. Francis Boyle: Well, what I would say is this. Right now, if you look at the article at the Wall Street Journal, big pharma is trying to sell all sorts of – they’re taking all their drugs off the shelf and say well let’s see if it works. Which is preposterous. Okay. The scientists are saying, well, we can get you a vaccine maybe two to three months but they’re not tested. So what we do know, however, is that Pirbright vaccine has been patented. So all I can assume is that that might work. But I don’t think I’d be taking any of these other vaccines. No, you have no idea what’s in there. You’ll be the Guinea pig for big pharma and everyone figures they’re gonna make a lot of money here. So I’ll keep my eye open on this and how it develop but I wouldn’t trust anything they’re trying to sell right now. They’re just pulling these things off the shelf.
If they do come up with something in two to three months, even that’s not going to be tested in accordance with normal scientific protocol. So it’s going to be a crap shoot. If it’s going to help you, indeed it might not help you because they’ll be using for this vaccines (these DNA genetic engineered vaccines) they’ll be using live coronavirus probably and sticking it in there and giving you some live coronavirus on the theory you’ll develop an immunity. That’s the way a lot of these vaccines worked out, that’s what happened with the Ebola vaccine that created the Ebola pandemic there in West Africa. They were testing out a vaccine on poor black Africans, as usual, and this vaccine had live Ebola in it so it gave them Ebola. So again, I’d be very careful even if they do come up with these vaccines two to three months from now, very careful. Why would you want to inject the live coronavirus in you?
Geopolitics and Empire: All right. I don’t believe you have a strong online presence. How can people best follow your work? I suppose to search for interviews as well as get your books.
Dr. Francis Boyle: Well, basically I’m blackballed and blacklisted off all the mainstream news media here on purpose. As far as I can figure out, the US government gave an order that I should not be interviewed by anyone, so I’m not. I guess you could just put my name in there under Google, Google alert, and some interviews might come up. What happened was, right after the anthrax attacks of 9/11 2001, I was giving a lecture out at Harvard m Alma Mater. I was running a panel on biological warfare for the council for responsible genetics and it was at Harvard Divinity School and as I was going in, there was a Fox camera crew there from Boston and I said it looks to me like this has come out of the US government lab. We know they do research and testing on anthrax. Then I said the same thing there at Harvard then I gave an interview to a radio station in Washington, D C then I gave an interview on that to the BBC. So the whole world saw it and at that point I was completely cut off and I’ve been cut off ever since. So you probably not going to hear too many interviews from me here. As for my book. Biowarfare & Terrorism, you can just get it at amazon.com. That picks up the story pretty much from 9/11 2001 and until it went to press and then there are interviews I’d given to an investigative reporter, Sherwood Ross and a big one I just sent you and you might want to put that on your web page. That was pretty comprehensive.
Geopolitics and Empire: Yeah, I read that as well and I’ll include the link in the description of this interview so people can go check that out. You’re not the only academic I know and have heard of others that similar things have happened and that’s just I guess the price we pay for telling the truth. Again, for listeners, if people wanted to have a broader context and deeper understanding of what’s happening today especially with biological warfare as well as us foreign policy and international affairs, I urge you to get Dr. Francis Boyle’s books and listen to his interviews as well as his colleagues book. Graeme Macqueen, The Anthrax Deception, The Case For Domestic Conspiracy. Thank you for being with us, Dr. Boyle.
Dr. Francis Boyle: Well, thank you and again, please understand these are my current opinions. I could change my opinion here based on more evidence. So I’m just looking at the evidence out there as I see it and you have to understand there is so much disinformation, lies and propaganda that it’s kind of very difficult to distinguish truth from fact. I’m doing the best job I can here.
Event 201
via centerforhealthsecurity
Event 201 simulates an outbreak of a novel zoonotic coronavirus transmitted from bats to pigs to people that eventually becomes efficiently transmissible from person to person, leading to a severe pandemic. The pathogen and the disease it causes are modeled largely on SARS, but it is more transmissible in the community setting by people with mild symptoms.
The disease starts in pig farms in Brazil, quietly and slowly at first, but then it starts to spread more rapidly in healthcare settings. When it starts to spread efficiently from person to person in the low-income, densely packed neighborhoods of some of the megacities in South America, the epidemic explodes. It is first exported by air travel to Portugal, the United States, and China and then to many other countries. Although at first some countries are able to control it, it continues to spread and be reintroduced, and eventually no country can maintain control.
There is no possibility of a vaccine being available in the first year. There is a fictional antiviral drug that can help the sick but not significantly limit spread of the disease.
Since the whole human population is susceptible, during the initial months of the pandemic, the cumulative number of cases increases exponentially, doubling every week. And as the cases and deaths accumulate, the economic and societal consequences become increasingly severe.
The scenario ends at the 18-month point, with 65 million deaths. The pandemic is beginning to slow due to the decreasing number of susceptible people. The pandemic will continue at some rate until there is an effective vaccine or until 80-90 % of the global population has been exposed. From that point on, it is likely to be an endemic childhood disease.
Event 201 simulates an outbreak of a novel zoonotic coronavirus transmitted from bats to pigs to people that eventually becomes efficiently transmissible from person to person, leading to a severe pandemic. The pathogen and the disease it causes are modeled largely on SARS, but it is more transmissible in the community setting by people with mild symptoms.
The disease starts in pig farms in Brazil, quietly and slowly at first, but then it starts to spread more rapidly in healthcare settings. When it starts to spread efficiently from person to person in the low-income, densely packed neighborhoods of some of the megacities in South America, the epidemic explodes. It is first exported by air travel to Portugal, the United States, and China and then to many other countries. Although at first some countries are able to control it, it continues to spread and be reintroduced, and eventually no country can maintain control.
There is no possibility of a vaccine being available in the first year. There is a fictional antiviral drug that can help the sick but not significantly limit spread of the disease.
Since the whole human population is susceptible, during the initial months of the pandemic, the cumulative number of cases increases exponentially, doubling every week. And as the cases and deaths accumulate, the economic and societal consequences become increasingly severe.
The scenario ends at the 18-month point, with 65 million deaths. The pandemic is beginning to slow due to the decreasing number of susceptible people. The pandemic will continue at some rate until there is an effective vaccine or until 80-90 % of the global population has been exposed. From that point on, it is likely to be an endemic childhood disease.
Testing of Coronavirus 'Cure' Set to Start in Australia in Weeks, First Participant in U.S. Vaccine Trial Due to Get First Dose Today
via Newsweek
By Kashmira Gander On 3/16/20 at 6:46 AM EDT
As the COVID-19 pandemic continues, scientists in Australia and the U.S. believe they are a step closer to developing a vaccine and treatment to fight the new coronavirus.
Professor David Paterson, director of the University of Queensland Centre for Clinical Research, told Australian website News.com.au that his team used two existing drugs to deactivate the new coronavirus named SARS-CoV- 2 (not to be confused with the virus which causes SARS), in test tubes. One drug is used against HIV and the other, called chloroquine, treats malaria.
Paterson said the HIV drug was given to some of the first patients to be diagnosed with COVID-19 in Australia, and caused the "disappearance of the virus." The patients have since recovered, he said.
The patients "all did very, very well when they were treated with the HIV drug.
"That's reassuring ... that we're onto something really good here," he said.
The drugs could be called a "treatment or a cure," and a "potentially effective treatment" if found to be effective, he said.
However, Paterson stressed it is important to test the drugs methodically "to give patients "the absolute best treatment rather than just someone's guesses or someone's anecdotal experiences from a few people."
"There have already been patients treated with these in Australia and there's been successful outcomes but it hasn't been done in a controlled or a comparative way," he said.
By the end of March, the team plans to have "very rapidly" enrolled COVID-19 patients on a clinical trial to test the treatment in 50 hospitals across Australia. They will investigate whether the drugs are most effective together or individually.
Meanwhile in the U.S., scientists are due to give a participant in a clinical trial for a vaccine against SARS-CoV-2 their first dose of the preparation on Monday, a government official to the Associated Press news agency on a condition of anonymity, as the decision had not been made public.
The trial is the first for a vaccine for SARS-CoV-2 in people, according to Kaiser Permanente Washington Health Research Institute in Seattle where it's being conducted. The investigational vaccine was created by the biotech company Moderna.
Participants can't be infected by the investigational vaccine called mRNA-1273 as it does not contain SARS-CoV-2, the institution said in a news release. Instead, it contains a genetic code made in a lab, which makes the process of developing the preparation faster.
Over a period of 14 months, a total of 45 participants will take part in the first phase of the trial which will test how safe different doses of the vaccine are, and whether it kicks the immune system into action. The scientists will investigate how effective the vaccine is later down the line. Participants in the trial are required to be aged between 18 to 55-years-old and can't have health conditions or take medications which affect the immune system. Each will receive a total of $1,100 for taking part in the trial.
Since the COVID-19 outbreak started in the central Chinese city of Wuhan late last year, over 169,000 cases have been confirmed and more than 77,000 people have recovered. A total of 6,513 people have died. As indicated in the map by Statista below the virus has reached every continent except Antarctica.
By Kashmira Gander On 3/16/20 at 6:46 AM EDT
As the COVID-19 pandemic continues, scientists in Australia and the U.S. believe they are a step closer to developing a vaccine and treatment to fight the new coronavirus.
Professor David Paterson, director of the University of Queensland Centre for Clinical Research, told Australian website News.com.au that his team used two existing drugs to deactivate the new coronavirus named SARS-CoV- 2 (not to be confused with the virus which causes SARS), in test tubes. One drug is used against HIV and the other, called chloroquine, treats malaria.
Paterson said the HIV drug was given to some of the first patients to be diagnosed with COVID-19 in Australia, and caused the "disappearance of the virus." The patients have since recovered, he said.
The patients "all did very, very well when they were treated with the HIV drug.
"That's reassuring ... that we're onto something really good here," he said.
The drugs could be called a "treatment or a cure," and a "potentially effective treatment" if found to be effective, he said.
However, Paterson stressed it is important to test the drugs methodically "to give patients "the absolute best treatment rather than just someone's guesses or someone's anecdotal experiences from a few people."
"There have already been patients treated with these in Australia and there's been successful outcomes but it hasn't been done in a controlled or a comparative way," he said.
By the end of March, the team plans to have "very rapidly" enrolled COVID-19 patients on a clinical trial to test the treatment in 50 hospitals across Australia. They will investigate whether the drugs are most effective together or individually.
Meanwhile in the U.S., scientists are due to give a participant in a clinical trial for a vaccine against SARS-CoV-2 their first dose of the preparation on Monday, a government official to the Associated Press news agency on a condition of anonymity, as the decision had not been made public.
The trial is the first for a vaccine for SARS-CoV-2 in people, according to Kaiser Permanente Washington Health Research Institute in Seattle where it's being conducted. The investigational vaccine was created by the biotech company Moderna.
Participants can't be infected by the investigational vaccine called mRNA-1273 as it does not contain SARS-CoV-2, the institution said in a news release. Instead, it contains a genetic code made in a lab, which makes the process of developing the preparation faster.
Over a period of 14 months, a total of 45 participants will take part in the first phase of the trial which will test how safe different doses of the vaccine are, and whether it kicks the immune system into action. The scientists will investigate how effective the vaccine is later down the line. Participants in the trial are required to be aged between 18 to 55-years-old and can't have health conditions or take medications which affect the immune system. Each will receive a total of $1,100 for taking part in the trial.
Since the COVID-19 outbreak started in the central Chinese city of Wuhan late last year, over 169,000 cases have been confirmed and more than 77,000 people have recovered. A total of 6,513 people have died. As indicated in the map by Statista below the virus has reached every continent except Antarctica.
Canada Investigates China’s Biological Espionage
By
GreatGameIndia -
August 8, 2019 | Last modified on February 29th, 2020 at 9:55 pm,
Canada has launched an investigation into China’s Biological Espionage. Bio-warfare experts question why Canada was sending lethal viruses to China.
In a table-top pandemic exercise at Johns Hopkins University last year, a pathogen based on the emerging Nipah virus was released by fictional extremists, killing 150 million people.
A less apocalyptic scenario mapped out by a blue-ribbon U.S. panel envisioned Nipah being dispersed by terrorists and claiming over 6,000 American lives.
Scientists from Canada’s National Microbiology Laboratory (NML) have also said the highly lethal bug is a potential bio-weapon.
But this March that same lab shipped samples of the henipavirus family and of Ebola to China, which has long been suspected of running a secretive biological warfare program.
China strongly denies it makes germ weapons, and Canadian officials say the shipment was part of its efforts to support public-health research worldwide. Sharing of such samples internationally is relatively standard practice.
But some experts are raising questions about the March transfer, which appears to be at the centre of a shadowy RCMP investigation and dismissal of a top scientist at the Winnipeg-based NML.
“I would say this Canadian ‘contribution’ might likely be counterproductive,” said Dany Shoham, a biological and chemical warfare expert at Israel’s Bar-Ilan University. “I think the Chinese activities … are highly suspicious, in terms of exploring (at least) those viruses as BW agents. “
James Giordano, a neurology professor at Georgetown University and senior fellow in biowarfare at the U.S. Special Operations Command, said it’s worrisome on a few fronts.
China’s growing investment in bio-science, looser ethics around gene-editing and other cutting-edge technology and integration between government and academia raise the spectre of such pathogens being weaponized, he said.
That could mean an offensive agent, or a modified germ let loose by proxies, for which only China has the treatment or vaccine, said Giordano, co-head of Georgetown’s Brain Science and Global Law and Policy Program.
“This is not warfare, per se,” he said. “But what it’s doing is leveraging the capability to act as global saviour, which then creates various levels of macro and micro economic and bio-power dependencies.”
Asked if the possibility of the Canadian germs being diverted into a Chinese bio weapons program is connected to other upheaval at the microbiology lab, Public Health Agency of Canada spokeswoman Anna Maddison said this week the agency “continues to look into the administrative matter.”
The agency divulged last week that it sent samples of Ebola and henipavirus — which includes Nipah and the related Hendra — to China in March. It was meant for virus research, part of the agency’s mission to back international public-health research, a spokesman said.
Last month, an acclaimed NML scientist — Xiangguo Qiu — was reportedly escorted out of the lab along with her husband, another biologist, and members of her research team. The agency said it was investigating an “administrative issue,” and had referred a possible policy breach to the RCMP. Little more has been said about the affair.
China has been a signatory to the Biological Weapons Convention since 1984, and has repeatedly insisted it is abiding by the treaty that bans developing bio-weapons.
But suspicions have persisted, with the U.S. State Department and other agencies stating publicly as recently as 2009 that they believe China has offensive biological agents.
Though no details have appeared in the open literature, China is “commonly considered to have an active biological warfare program,” says the Federation of American Scientists. An official with the U.S. Army Medical Research Institute of Chemical Defence charged last month China is the world leader in toxin “threats.”
In a 2015 academic paper, Shoham – of Bar-Ilan’s Begin-Sadat Center for Strategic Studies – asserts that more than 40 Chinese facilities are involved in bio-weapon production.
China’s Academy of Military Medical Sciences actually developed an Ebola drug – called JK-05 — but little has been divulged about it or the defence facility’s possession of the virus, prompting speculation its Ebola cells are part of China’s bio-warfare arsenal, Shoham told the National Post.
Ebola is classified as a “category A” bioterrorism agent by the U.S. Centers for Disease Control and Prevention, meaning it could be easily transmitted from person to person, would result in high death rates and “might cause panic.” The CDC lists Nipah as a category C substance, a deadly emerging pathogen that could be engineered for mass dissemination.
Nipah, which was first seen in Malaysia in 1998, has caused a series of outbreaks across east and south Asia, with death rates mostly over 50 per cent, and as high as 100 per cent, according to World Health Organization figures. It can cause encephalitis, an often-fatal brain swelling, and has no known treatment or vaccine.
The Johns Hopkins exercise — called Clade X — involved a version of Nipah modified to be more easily passed between people. America’s Blue Ribbon Study Panel on Biodefence prefaced its 2015 report with a scenario involving the intentional release of Nipah by aerosol spray.
China’s extensive and controversial use of CRISPR gene-editing and weaponizing Biotechnology makes it conceivable the country could bio-engineer germs like Nipah to make them even more dangerous, Giordano said.
GreatGameIndia -
August 8, 2019 | Last modified on February 29th, 2020 at 9:55 pm,
Canada has launched an investigation into China’s Biological Espionage. Bio-warfare experts question why Canada was sending lethal viruses to China.
In a table-top pandemic exercise at Johns Hopkins University last year, a pathogen based on the emerging Nipah virus was released by fictional extremists, killing 150 million people.
A less apocalyptic scenario mapped out by a blue-ribbon U.S. panel envisioned Nipah being dispersed by terrorists and claiming over 6,000 American lives.
Scientists from Canada’s National Microbiology Laboratory (NML) have also said the highly lethal bug is a potential bio-weapon.
But this March that same lab shipped samples of the henipavirus family and of Ebola to China, which has long been suspected of running a secretive biological warfare program.
China strongly denies it makes germ weapons, and Canadian officials say the shipment was part of its efforts to support public-health research worldwide. Sharing of such samples internationally is relatively standard practice.
But some experts are raising questions about the March transfer, which appears to be at the centre of a shadowy RCMP investigation and dismissal of a top scientist at the Winnipeg-based NML.
“I would say this Canadian ‘contribution’ might likely be counterproductive,” said Dany Shoham, a biological and chemical warfare expert at Israel’s Bar-Ilan University. “I think the Chinese activities … are highly suspicious, in terms of exploring (at least) those viruses as BW agents. “
James Giordano, a neurology professor at Georgetown University and senior fellow in biowarfare at the U.S. Special Operations Command, said it’s worrisome on a few fronts.
China’s growing investment in bio-science, looser ethics around gene-editing and other cutting-edge technology and integration between government and academia raise the spectre of such pathogens being weaponized, he said.
That could mean an offensive agent, or a modified germ let loose by proxies, for which only China has the treatment or vaccine, said Giordano, co-head of Georgetown’s Brain Science and Global Law and Policy Program.
“This is not warfare, per se,” he said. “But what it’s doing is leveraging the capability to act as global saviour, which then creates various levels of macro and micro economic and bio-power dependencies.”
Asked if the possibility of the Canadian germs being diverted into a Chinese bio weapons program is connected to other upheaval at the microbiology lab, Public Health Agency of Canada spokeswoman Anna Maddison said this week the agency “continues to look into the administrative matter.”
The agency divulged last week that it sent samples of Ebola and henipavirus — which includes Nipah and the related Hendra — to China in March. It was meant for virus research, part of the agency’s mission to back international public-health research, a spokesman said.
Last month, an acclaimed NML scientist — Xiangguo Qiu — was reportedly escorted out of the lab along with her husband, another biologist, and members of her research team. The agency said it was investigating an “administrative issue,” and had referred a possible policy breach to the RCMP. Little more has been said about the affair.
China has been a signatory to the Biological Weapons Convention since 1984, and has repeatedly insisted it is abiding by the treaty that bans developing bio-weapons.
But suspicions have persisted, with the U.S. State Department and other agencies stating publicly as recently as 2009 that they believe China has offensive biological agents.
Though no details have appeared in the open literature, China is “commonly considered to have an active biological warfare program,” says the Federation of American Scientists. An official with the U.S. Army Medical Research Institute of Chemical Defence charged last month China is the world leader in toxin “threats.”
In a 2015 academic paper, Shoham – of Bar-Ilan’s Begin-Sadat Center for Strategic Studies – asserts that more than 40 Chinese facilities are involved in bio-weapon production.
China’s Academy of Military Medical Sciences actually developed an Ebola drug – called JK-05 — but little has been divulged about it or the defence facility’s possession of the virus, prompting speculation its Ebola cells are part of China’s bio-warfare arsenal, Shoham told the National Post.
Ebola is classified as a “category A” bioterrorism agent by the U.S. Centers for Disease Control and Prevention, meaning it could be easily transmitted from person to person, would result in high death rates and “might cause panic.” The CDC lists Nipah as a category C substance, a deadly emerging pathogen that could be engineered for mass dissemination.
Nipah, which was first seen in Malaysia in 1998, has caused a series of outbreaks across east and south Asia, with death rates mostly over 50 per cent, and as high as 100 per cent, according to World Health Organization figures. It can cause encephalitis, an often-fatal brain swelling, and has no known treatment or vaccine.
The Johns Hopkins exercise — called Clade X — involved a version of Nipah modified to be more easily passed between people. America’s Blue Ribbon Study Panel on Biodefence prefaced its 2015 report with a scenario involving the intentional release of Nipah by aerosol spray.
China’s extensive and controversial use of CRISPR gene-editing and weaponizing Biotechnology makes it conceivable the country could bio-engineer germs like Nipah to make them even more dangerous, Giordano said.
Inside the Chinese lab poised to study world's most dangerous pathogens
via Nature
Maximum-security biolab is part of plan to build network of BSL-4 facilities across China.
A laboratory in Wuhan is on the cusp of being cleared to work with the world’s most dangerous pathogens. The move is part of a plan to build between five and seven biosafety level-4 (BSL-4) labs across the Chinese mainland by 2025, and has generated much excitement, as well as some concerns.
Some scientists outside China worry about pathogens escaping, and the addition of a biological dimension to geopolitical tensions between China and other nations. But Chinese microbiologists are celebrating their entrance to the elite cadre empowered to wrestle with the world’s greatest biological threats.
“It will offer more opportunities for Chinese researchers, and our contribution on the BSL‑4-level pathogens will benefit the world,” says George Gao, director of the Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology in Beijing. There are already two BSL-4 labs in Taiwan, but the National Bio-safety Laboratory, Wuhan, would be the first on the Chinese mainland.
The lab was certified as meeting the standards and criteria of BSL-4 by the China National Accreditation Service for Conformity Assessment (CNAS) in January. The CNAS examined the lab’s infrastructure, equipment and management, says a CNAS representative, paving the way for the Ministry of Health to give its approval. A representative from the ministry says it will move slowly and cautiously; if the assessment goes smoothly, it could approve the laboratory by the end of June.
BSL-4 is the highest level of biocontainment: its criteria include filtering air and treating water and waste before they leave the laboratory, and stipulating that researchers change clothes and shower before and after using lab facilities. Such labs are often controversial. The first BSL-4 lab in Japan was built in 1981, but operated with lower-risk pathogens until 2015, when safety concerns were finally overcome.
The expansion of BSL-4-lab networks in the United States and Europe over the past 15 years — with more than a dozen now in operation or under construction in each region — also met with resistance, including questions about the need for so many facilities.
The Wuhan lab cost 300 million yuan (US$44 million), and to allay safety concerns it was built far above the flood plain and with the capacity to withstand a magnitude-7 earthquake, although the area has no history of strong earthquakes. It will focus on the control of emerging diseases, store purified viruses and act as a World Health Organization ‘reference laboratory’ linked to similar labs around the world. “It will be a key node in the global biosafety-lab network,” says lab director Yuan Zhiming.
The Chinese Academy of Sciences approved the construction of a BSL-4 laboratory in 2003, and the epidemic of SARS (severe acute respiratory syndrome) around the same time lent the project momentum. The lab was designed and constructed with French assistance as part of a 2004 cooperative agreement on the prevention and control of emerging infectious diseases. But the complexity of the project, China’s lack of experience, difficulty in maintaining funding and long government approval procedures meant that construction wasn’t finished until the end of 2014.
The lab’s first project will be to study the BSL-3 pathogen that causes Crimean–Congo haemorrhagic fever: a deadly tick-borne virus that affects livestock across the world, including in northwest China, and that can jump to people.
Future plans include studying the pathogen that causes SARS, which also doesn’t require a BSL-4 lab, before moving on to Ebola and the West African Lassa virus, which do. Some one million Chinese people work in Africa; the country needs to be ready for any eventuality, says Yuan. “Viruses don’t know borders.”
Gao travelled to Sierra Leone during the recent Ebola outbreak, allowing his team to report the speed with which the virus mutated into new strains1. The Wuhan lab will give his group a chance to study how such viruses cause disease, and to develop treatments based on antibodies and small molecules, he says.
The opportunities for international collaboration, meanwhile, will aid the genetic analysis and epidemiology of emergent diseases. “The world is facing more new emerging viruses, and we need more contribution from China,” says Gao. In particular, the emergence of zoonotic viruses — those that jump to humans from animals, such as SARS or Ebola — is a concern, says Bruno Lina, director of the VirPath virology lab in Lyon, France.
Many staff from the Wuhan lab have been training at a BSL-4 lab in Lyon, which some scientists find reassuring. And the facility has already carried out a test-run using a low-risk virus.
But worries surround the Chinese lab, too. The SARS virus has escaped from high-level containment facilities in Beijing multiple times, notes Richard Ebright, a molecular biologist at Rutgers University in Piscataway, New Jersey. Tim Trevan, founder of CHROME Biosafety and Biosecurity Consulting in Damascus, Maryland, says that an open culture is important to keeping BSL-4 labs safe, and he questions how easy this will be in China, where society emphasizes hierarchy. “Diversity of viewpoint, flat structures where everyone feels free to speak up and openness of information are important,” he says.
Yuan says that he has worked to address this issue with staff. “We tell them the most important thing is that they report what they have or haven’t done,” he says. And the lab’s international collaborations will increase openness. “Transparency is the basis of the lab,” he adds.
The plan to expand into a network heightens such concerns. One BSL-4 lab in Harbin is already awaiting accreditation; the next two are expected to be in Beijing and Kunming, the latter focused on using monkey models to study disease.
Lina says that China’s size justifies this scale, and that the opportunity to combine BSL-4 research with an abundance of research monkeys — Chinese researchers face less red tape than those in the West when it comes to research on primates — could be powerful. “If you want to test vaccines or antivirals, you need a non-human primate model,” says Lina.
But Ebright is not convinced of the need for more than one BSL-4 lab in mainland China. He suspects that the expansion there is a reaction to the networks in the United States and Europe, which he says are also unwarranted. He adds that governments will assume that such excess capacity is for the potential development of bioweapons.
“These facilities are inherently dual use,” he says. The prospect of ramping up opportunities to inject monkeys with pathogens also worries, rather than excites, him: “They can run, they can scratch, they can bite.”
Trevan says China’s investment in a BSL-4 lab may, above all, be a way to prove to the world that the nation is competitive. “It is a big status symbol in biology,” he says, “whether it’s a need or not.”
Nature
542,
399–400
(23 February 2017)
doi:10.1038/nature.2017.21487
Maximum-security biolab is part of plan to build network of BSL-4 facilities across China.
A laboratory in Wuhan is on the cusp of being cleared to work with the world’s most dangerous pathogens. The move is part of a plan to build between five and seven biosafety level-4 (BSL-4) labs across the Chinese mainland by 2025, and has generated much excitement, as well as some concerns.
Some scientists outside China worry about pathogens escaping, and the addition of a biological dimension to geopolitical tensions between China and other nations. But Chinese microbiologists are celebrating their entrance to the elite cadre empowered to wrestle with the world’s greatest biological threats.
“It will offer more opportunities for Chinese researchers, and our contribution on the BSL‑4-level pathogens will benefit the world,” says George Gao, director of the Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology in Beijing. There are already two BSL-4 labs in Taiwan, but the National Bio-safety Laboratory, Wuhan, would be the first on the Chinese mainland.
The lab was certified as meeting the standards and criteria of BSL-4 by the China National Accreditation Service for Conformity Assessment (CNAS) in January. The CNAS examined the lab’s infrastructure, equipment and management, says a CNAS representative, paving the way for the Ministry of Health to give its approval. A representative from the ministry says it will move slowly and cautiously; if the assessment goes smoothly, it could approve the laboratory by the end of June.
BSL-4 is the highest level of biocontainment: its criteria include filtering air and treating water and waste before they leave the laboratory, and stipulating that researchers change clothes and shower before and after using lab facilities. Such labs are often controversial. The first BSL-4 lab in Japan was built in 1981, but operated with lower-risk pathogens until 2015, when safety concerns were finally overcome.
The expansion of BSL-4-lab networks in the United States and Europe over the past 15 years — with more than a dozen now in operation or under construction in each region — also met with resistance, including questions about the need for so many facilities.
The Wuhan lab cost 300 million yuan (US$44 million), and to allay safety concerns it was built far above the flood plain and with the capacity to withstand a magnitude-7 earthquake, although the area has no history of strong earthquakes. It will focus on the control of emerging diseases, store purified viruses and act as a World Health Organization ‘reference laboratory’ linked to similar labs around the world. “It will be a key node in the global biosafety-lab network,” says lab director Yuan Zhiming.
The Chinese Academy of Sciences approved the construction of a BSL-4 laboratory in 2003, and the epidemic of SARS (severe acute respiratory syndrome) around the same time lent the project momentum. The lab was designed and constructed with French assistance as part of a 2004 cooperative agreement on the prevention and control of emerging infectious diseases. But the complexity of the project, China’s lack of experience, difficulty in maintaining funding and long government approval procedures meant that construction wasn’t finished until the end of 2014.
The lab’s first project will be to study the BSL-3 pathogen that causes Crimean–Congo haemorrhagic fever: a deadly tick-borne virus that affects livestock across the world, including in northwest China, and that can jump to people.
Future plans include studying the pathogen that causes SARS, which also doesn’t require a BSL-4 lab, before moving on to Ebola and the West African Lassa virus, which do. Some one million Chinese people work in Africa; the country needs to be ready for any eventuality, says Yuan. “Viruses don’t know borders.”
Gao travelled to Sierra Leone during the recent Ebola outbreak, allowing his team to report the speed with which the virus mutated into new strains1. The Wuhan lab will give his group a chance to study how such viruses cause disease, and to develop treatments based on antibodies and small molecules, he says.
The opportunities for international collaboration, meanwhile, will aid the genetic analysis and epidemiology of emergent diseases. “The world is facing more new emerging viruses, and we need more contribution from China,” says Gao. In particular, the emergence of zoonotic viruses — those that jump to humans from animals, such as SARS or Ebola — is a concern, says Bruno Lina, director of the VirPath virology lab in Lyon, France.
Many staff from the Wuhan lab have been training at a BSL-4 lab in Lyon, which some scientists find reassuring. And the facility has already carried out a test-run using a low-risk virus.
But worries surround the Chinese lab, too. The SARS virus has escaped from high-level containment facilities in Beijing multiple times, notes Richard Ebright, a molecular biologist at Rutgers University in Piscataway, New Jersey. Tim Trevan, founder of CHROME Biosafety and Biosecurity Consulting in Damascus, Maryland, says that an open culture is important to keeping BSL-4 labs safe, and he questions how easy this will be in China, where society emphasizes hierarchy. “Diversity of viewpoint, flat structures where everyone feels free to speak up and openness of information are important,” he says.
Yuan says that he has worked to address this issue with staff. “We tell them the most important thing is that they report what they have or haven’t done,” he says. And the lab’s international collaborations will increase openness. “Transparency is the basis of the lab,” he adds.
The plan to expand into a network heightens such concerns. One BSL-4 lab in Harbin is already awaiting accreditation; the next two are expected to be in Beijing and Kunming, the latter focused on using monkey models to study disease.
Lina says that China’s size justifies this scale, and that the opportunity to combine BSL-4 research with an abundance of research monkeys — Chinese researchers face less red tape than those in the West when it comes to research on primates — could be powerful. “If you want to test vaccines or antivirals, you need a non-human primate model,” says Lina.
But Ebright is not convinced of the need for more than one BSL-4 lab in mainland China. He suspects that the expansion there is a reaction to the networks in the United States and Europe, which he says are also unwarranted. He adds that governments will assume that such excess capacity is for the potential development of bioweapons.
“These facilities are inherently dual use,” he says. The prospect of ramping up opportunities to inject monkeys with pathogens also worries, rather than excites, him: “They can run, they can scratch, they can bite.”
Trevan says China’s investment in a BSL-4 lab may, above all, be a way to prove to the world that the nation is competitive. “It is a big status symbol in biology,” he says, “whether it’s a need or not.”
Nature
542,
399–400
(23 February 2017)
doi:10.1038/nature.2017.21487
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